5-Methylsulfanyl-3-propan-2-yl-1,2,4-oxadiazole

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 5-Methylsulfanyl-3-propan-2-yl-1,2,4-oxadiazole
• 英文别名: 5-methylsulfanyl-3-propan-2-yl-1,2,4-oxadiazole
• 化学式: C₆H₁₀N₂OS
• 分子量: 158.22
• InChiKey: RUCVYECVTOBHAL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  64.2
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Modulators of the integrated stress pathway
  申请人：Calico Life Sciences LLC

  公开号：US10864196B2

  公开（公告）日：2020-12-15

  Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases; disorders and conditions.

  本文提供了用于调节综合应激反应（ISR）和治疗相关疾病、失调和病症的化合物、组合物和方法。
• MODULATORS OF THE INTEGRATED STRESS PATHWAY
  申请人：Calico Life Sciences LLC

  公开号：US20190142806A1

  公开（公告）日：2019-05-16

  Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases; disorders and conditions.
• NOVEL AGENTS TARGETING INHIBITOR OF APOPTOSIS PROTEINS
  申请人：The Regents of the University of California

  公开号：US20200345804A1

  公开（公告）日：2020-11-05

  Disclosed herein, inter alia, are methods of use and composition of novel inhibitors that target the Smac binding site of a variety of inhibitor of apoptosis proteins that contain a Bir domain, including XIAP, cIAP1, cIAP2, or other IAP proteins.