3-Allyl-2-allyloxy-benzamid | 91956-95-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-Allyl-2-allyloxy-benzamid
• 英文别名: 3-Allyl-2-allyloxybenzamide；2-prop-2-enoxy-3-prop-2-enylbenzamide
• CAS: 91956-95-5
• 化学式: C₁₃H₁₅NO₂
• 分子量: 217.268
• InChiKey: ZLVGTTKNVZEGIM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  52.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• PROCESS FOR THE PRODUCTION OF FUSED, TRICYCLIC SULFONAMIDES
  申请人：Elan Pharmaceuticals Inc.

  公开号：EP2411388A2

  公开（公告）日：2012-02-01
• [EN] PROCESS FOR THE PRODUCTION OF FUSED, TRICYCLIC SULFONAMIDES<br/>[FR] PROCÉDÉ DE PRODUCTION DE SULFONAMIDES TRICYCLIQUES FUSIONNÉS
  申请人：ELAN PHARM INC

  公开号：WO2010111418A2

  公开（公告）日：2010-09-30

  The present invention provides methods, i.e., scalable or large-scale processes for the production of fused, tricyclic sulfonamido analogs, such as substituted or unsubstituted 5- (aryl-sulfonyl)-4,5-dihydro- 1H-pyrazolo[4,3-c]quinolines and 5-(heteroaryl-sulfonyl)-4,5- dihydro-1H-pyrazolo[4,3-c]quinolines. Exemplary methods of the invention include an intra-molecular cyclization step, in which a carbon-nitrogen bond is formed, and which employs a copper-based catalyst that contains at least one organic ligand, such as DMEDA. The invention further provides compounds, which are useful as intermediates in the methods of the invention.