(alpha-Methylphenethyl)hydrazine sulfate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (alpha-Methylphenethyl)hydrazine sulfate
• 英文别名: 1-phenylpropan-2-ylhydrazine;sulfuric acid
• 化学式: C9H16N2O4S
• 分子量: 248.3
• InChiKey: GSQFLDMTPDBFCI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.43
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  121
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• Drug delivery device
  申请人：Merck & Co., Inc.

  公开号：EP0147780A2

  公开（公告）日：1985-07-10

  Polyvinyl alcohol for use as a film coating, a matrix for monolithic device or as a barrier coating for the preparation of controlled release drug delivery systems.

  聚乙烯醇，可用作薄膜涂层、整体装置的基质或阻隔涂层，用于制备控释给药系统。
• A system for enhancing the water dissolution rate and solubility of poorly soluble drugs
  申请人：Merck & Co., Inc.

  公开号：EP0179583A1

  公开（公告）日：1986-04-30

  Novel anhydrous compositions comprise a poorly water-soluble drug and a surfactant having enhanced dissolution rate and solubility. The drug-surfactant ratio in the composition is such that dissolution and solubility of the drug are enhanced. The compositions disclosed herein are useful in the treatment of patients (human and veterinary) as well as domestically and in agriculture.

  新型无水组合物由水溶性较差的药物和溶解速率和溶解度均有所提高的表面活性剂组成。组合物中的药物-表面活性剂比例可提高药物的溶解度和可溶性。本文公开的组合物可用于治疗病人（人类和兽医），也可用于国内和农业。
• METHODS AND COMPOSITIONS FOR SLEEP DISORDERS AND OTHER DISORDERS
  申请人：INTRA-CELLULAR THERAPIES INC.

  公开号：US20140050783A1

  公开（公告）日：2014-02-20

  Use of particular substituted heterocycle fused gamma-carboline compounds as pharmaceuticals and pharmaceutical compositions comprising them for the treatment of one or more disorders involving the 5-HT2A, SERT and/or dopamine D2 pathways are disclosed. In addition, the compounds may be combined with other therapeutic agents for the treatment of one or more sleep disorders, depression, psychosis, dyskinesias, and/or Parkinson's disease or any combinations.
• US4477470A
  申请人：——

  公开号：US4477470A

  公开（公告）日：1984-10-16
• US9168258B2
  申请人：——

  公开号：US9168258B2

  公开（公告）日：2015-10-27