2-(2-Ethyl-3-methylphenyl)ethanamine

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(2-Ethyl-3-methylphenyl)ethanamine
• 英文别名: 2-(2-ethyl-3-methylphenyl)ethanamine
• 化学式: C₁₁H₁₇N
• 分子量: 163.26
• InChiKey: PTALNQHYBJCLON-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• METHODS OF CANCER DETECTION USING PARPI-FL
  申请人：Memorial Sloan Kettering Cancer Center

  公开号：US20190046665A1

  公开（公告）日：2019-02-14

  The present disclosure describes methods of use of a composition comprising PARPi-fl to be administered to the oral cavity (e.g., via topical application to surfaces of the oral cavity) followed by imaging of the oral cavity for detection of squamous cell carcinoma of the oral cavity (e.g., in vivo, e.g., in a dental office setting or intraoperatively). The results disclosed herein show that topically applied PARPi-fl and subsequent intraoperative imaging of oral cavities can improve surgical removal of squamous cell carcinoma cells compared to healthy cells.