A pathogenic substance removing material and a blood filter comprising said material
申请人:TERUMO KABUSHIKI KAISHA
公开号:EP0586268A1
公开(公告)日:1994-03-09
A material wherein a polyamine compound is immobilized on its base surface and a blood filter using this material. The material is provided in the form of a porous membrane having the maximum pore diameter of 0.1 - 50 µm. The polyamine compound is at least one compound selected from the group consisting of (a) a polyamine compound which has primary and secondary amines in its molecule and a hydrophobic part between these amines, (b) a polyamine compound represented by the following formula (I);
wherein R¹, R², R³, R⁴ and R⁵ represent hydrogen, aliphatic and aromatic hydrocarbons, and halogen, and n is 5 or more, and (c) a polyamine compound represented by the following formula (II);
wherein R represents NH₂ or aminoalkyl radical having 1 to 4 carbon atoms and n is 5 or more. The blood filter comprises a housing which has an inlet and outlet, and the material arranged inside the housing.
一种在其基面上固定多胺化合物的材料和一种使用这种材料的血液过滤器。该材料以多孔膜的形式提供,其最大孔径为 0.1 - 50 µm。多胺化合物是至少一种选自以下组别的化合物:(a)分子中含有伯胺和仲胺以及在这些胺之间有疏水部分的多胺化合物;(b)由下式(I)表示的多胺化合物;(c)由下式(I)表示的多胺化合物;(d)由下式(I)表示的多胺化合物;
其中 R¹、R²、R³、R⁴ 和 R⁵ 代表氢、脂肪烃、芳香烃和卤素,n 为 5 或更多,以及 (c) 下式(II)所代表的多胺化合物;
其中 R 代表 NH₂或具有 1 至 4 个碳原子的氨基烷基,n 为 5 或更多。血液过滤器包括一个具有入口和出口的壳体,以及布置在壳体内的材料。