azidomethyl benzamidoxime

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: azidomethyl benzamidoxime
• 英文别名: N'-(azidomethyl)-N-hydroxybenzenecarboximidamide
• 化学式: C₈H₉N₅O
• 分子量: 191.192
• InChiKey: JLAPXGZGICXTJG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  59
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Novel compounds that inhibit tryptase activity
  申请人：MORPHOCHEM AG

  公开号：US20020137687A1

  公开（公告）日：2002-09-26

  The present invention relates to compounds of the Formula 1 or a pharmaceutically acceptable salt, solvate, hydrate or formulation thereof. These compounds can be used for the inhibition of tryptase and for the treatment and/or prevention of diseases that are mediated by tryptase activity.

  本发明涉及公式1的化合物或其药学上可接受的盐、溶剂化合物、水合物或制剂。这些化合物可用于抑制组胺酶和治疗和/或预防由组胺酶活性介导的疾病。
• COMPOUNDS THAT INHIBIT TRYPTASE ACTIVITY
  申请人：Morphochem AG

  公开号：EP1206444A1

  公开（公告）日：2002-05-22
• [EN] COMPOUNDS THAT INHIBIT TRYPTASE ACTIVITY<br/>[FR] COMPOSES INHIBITEURS DE L'ACTION DE LA TRYPTASE
  申请人：MORPHOCHEM AG

  公开号：WO2001014320A1

  公开（公告）日：2001-03-01

  The present invention relates to compounds of Formula (I) or a pharmaceutically acceptable salt, solvate, hydrate or formulation thereof. These compounds can be used for the inhibition of tryptase and for the treatment and/or prevention of diseases that are mediated by tryptase activity.