N-(but-2-enoxymethyl)-2-chloro-N-(2,6-diethylphenyl)acetamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(but-2-enoxymethyl)-2-chloro-N-(2,6-diethylphenyl)acetamide
• 化学式: C₁₇H₂₄ClNO₂
• 分子量: 309.8
• InChiKey: HZDIJTXDRLNTIS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  21
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  29.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Fungicides
  申请人：——

  公开号：US20030060626A1

  公开（公告）日：2003-03-27

  The invention provides fungicidal compounds of formula (I) or stereoisomers thereof: 1 wherein X is CH 2 O; A is hydrogen; E is hydrogen; q is 1; any two of K, L and M are nitrogen and the other is CH; T is oxygen or sulfur; and Z is an optionally substituted phenyl group or an optionally substituted heterocyclyl group.

  该发明提供了公式（I）或其立体异构体的杀真菌化合物：其中X为CH2O；A为氢；E为氢；q为1；K、L和M中的任意两个为氮，另一个为CH；T为氧或硫；Z为可选取代的苯基或可选取代的杂环基。
• Fungicidal acylaminbezamides, their production and use
  申请人：ZENECA LIMITED

  公开号：EP0468682A1

  公开（公告）日：1992-01-29

  Fungicidal compounds of formula (I): in which D and E are independently H or fluoro; X and Y are O or S; A, B, R³ and R⁴ have various specified values R¹ is C₂₋₄ alkenyl (optionally substituted with halogen), C₂₋₄ alkynyl (optionally substituted with halogen), halo(C₁₋₄)alkyl, C₃₋₆ cycloalkyl, C₃₋₆ cycloalkyl(C₁₋₄)alkyl, C₁₋₄ alkoxy(C₁₋₄)alkyl, C₁₋₄ alkylthio(C₁₋₄)alkyl or cyano; and R² is C₁₋₄ alkyl, C₁₋₄ alkoxy, C₂₋₄ alkenyl (optionally substituted with halogen), C₂₋₄ alkynyl (optionally substituted with halogen), halo(C₁₋₄) alkyl, C₃₋₆ cycloalkyl, C₃₋₆ cycloalkyl(C₁₋₄)alkyl, C₁₋₄alkoxy(C₁₋₄)alkyl, C₁₋₄ alkylthio(C₁₋₄)alkyl or cyano.

  化合物的杀菌成分公式（I）：其中D和E独立地为H或氟；X和Y为O或S；A、B、R³和R⁴具有不同的指定值，R¹为C₂₋₄烯基（可选择用卤素取代）、C₂₋₄炔基（可选择用卤素取代）、卤（C₁₋₄）烷基、C₃₋₆环烷基、C₃₋₆环烷基（C₁₋₄）烷基、C₁₋₄烷氧基（C₁₋₄）烷基、C₁₋₄烷基硫基（C₁₋₄）烷基或氰基；R²为C₁₋₄烷基、C₁₋₄烷氧基、C₂₋₄烯基（可选择用卤素取代）、C₂₋₄炔基（可选择用卤素取代）、卤（C₁₋₄）烷基、C₃₋₆环烷基、C₃₋₆环烷基（C₁₋₄）烷基、C₁₋₄烷氧基（C₁₋₄）烷基、C₁₋₄烷基硫基（C₁₋₄）烷基或氰基。
• FUNGICIDES
  申请人：——

  公开号：US20040092746A1

  公开（公告）日：2004-05-13

  The invention provides fungicidal compounds of formula (I) or stereoisomers thereof: 1 wherein X is CH 2 O; A is hydrogen; E is hydrogen; q is 1; any two of K, L and M are nitrogen and the other is CH; T is oxygen or sulfur; and Z is an optionally substituted phenyl group or an optionally substituted heterocyclyl group.

  该发明提供了式（I）或其立体异构体的杀真菌化合物：1其中X为CH2O；A为氢；E为氢；q为1；K、L和M中的任意两个为氮，另一个为CH；T为氧或硫；Z为可选取代的苯基或可选取代的杂环基。
• Pyridyl cyclopropane derivatives with fungicidal activity
  申请人：ZENECA LIMITED

  公开号：EP0436348A2

  公开（公告）日：1991-07-10

  Compounds of having the general formula (I): and stereoisomers thereof, wherein R¹ is hydrogen, halogen, C₁₋₄ alkoxy, C₁₋₄ alkyl, C₂₋₄ alkenyl, C₂₋₄ alkynyl, C₁₋₄ haloalkyl, C₁₋₄ haloalkoxy, COR or cyano; R², R³ and R⁴ are independently hydrogen, halogen or methyl, provided that R², R³ and R⁴ are not all hydrogen and provided that when one of them is methyl then at least one of the other two is not hydrogen; wherein R⁵ is hydrogen, C₁₋₄ alkyl (optionally substituted by hydrogen or cyano), optionally substituted benzyl, C₂₋₄ alkenyl, C₂₋₄ alkynyl, cyano, COR C₁₋₄ thioalkoxy C₁₋₄ thiohaloalkoxy or SNR⁷R⁸; R⁷ and R⁸ are independently C₁₋₄ alkyl or CO₂R; Y is oxygen or sulphur; R⁶ is C₁₋₄ alkoxy, C₁₋₄ thioalkoxy or -NR⁹ R¹⁰ ; and R⁹ and R¹⁰ are independently hydrogen, C₁₋₄ alkyl, aryl or aralkyl or R⁹ and R¹⁰ join to form an optionally substituted heterocyclic ring and R is C₁₋₄ alkyl or C₃₋₇ cycloalkyl. These compounds are fungicidally active.

  具有通式(I)的化合物： 及其立体异构体，其中 R¹ 是氢、卤素、C₁₋₄ 烷氧基、C₁₋₄ 烷基、C₂₋₄ 烯基、C₂₋₄ 炔基、C₁₋₄ 卤代烷基、C₁₋₄ 卤代烷氧基、COR 或氰基；R²、R³ 和 R⁴ 独立地是氢、卤素或甲基，但 R²、R³ 和 R⁴ 并非都是氢，而且当其中一个是甲基时，另外两个中至少有一个不是氢； 其中 R⁵ 是氢、C₁₋₄ 烷基（任选被氢或氰基取代）、任选被取代的苄基、C₂₋₄ 烯基、C₂₋₄ 炔基、氰基、COR C₁₋₄ 硫代烷氧基 C₁₋₄ 硫代烷氧基或 SNR⁷R⁸；R⁷ 和 R⁸ 独立地为 C₁₋₄ 烷基或 CO₂R；Y 是氧或硫； R⁶ 是 C₁₋₄ 烷氧基、C₁₋₄ 硫代烷氧基或 -NR⁹ R¹⁰ ；且 R𠞙 和 R¹⁰ 独立为氢、C₁₋₄ 烷基、芳基或芳烷基，或 R𠞙 和 R¹⁰ 连接形成任选取代的杂环，且 R 是 C₁₋₄ 烷基或 C₃₋₇ 环烷基。这些化合物具有杀真菌活性。
• Acylaminopyridinecarboxamides, process for their preparation and their use as fungicides
  申请人：ZENECA LIMITED

  公开号：EP0473267A2

  公开（公告）日：1992-03-04

  Fungicidal compounds of formula (I): in which A is fluoro, chloro, bromo, iodo, C₁₋₄ alkyl, C₁₋₄ alkoxy, halo(C₁₋₄)alkyl, C₁₋₄ alkoxylmethyl, C₁₋₄ alkylthiomethyl, C₂₋₄ alkenyl, C₂₋₄ alkynyl, C₁₋₄ alkoxycarbonyl, C₁₋₄ alkylcarbonyl, formyl, cyano, nitro or C₁₋₄ alkylthio; R¹ and R² are independently C₁₋₄ alkyl, C₃₋₆ alkenyl (optionally substituted with halogen), C₃₋₆ alkynyl (optionally substituted with halogen) C₁₋₄ alkoxy, halo(C₁₋₄)-alkyl, C₃₋₆ cycloalkyl, C₃₋₆ cycloalky(C₁₋₄)alkyl, C₁₋₄alkoxy(C₁₋₄)-alkyl, C₁₋₄ alkylthio(C₁₋₄)alkyl or cyano, or R¹ and R² together with the nitrogen to which they are atached join to form a morpholine, piperidine, pyrrolidine or azetidine ring, which may be optionally substitued with C₁₋₄ alkyl; R³ is H, or R³ and R⁴, together with the group C(0)N to which they are attached join to form an azetidin-2-one ring which is optionally substituted with C₁₋₄ alkyl; R⁴ is C₂₋₈ alkyl, C₂₋₈ alkenyl, C₂₋₈ alkynyl, or C₃₋₆ cycloalkyl, all of which may be optionally substituted with halogen, C₁₋₄ alkyl, C₁₋₄ alkoxy, C₁₋₄ alkylthio, cyano, C₁₋₄ alkylcarbonyl, C₁₋₄ alkoxycarbonyl, azido, nitro, isocyano or NR⁵R⁶ (where R⁵ and R⁶ are independently H, C₁₋₄ alkyl, C₁₋₄ alkylcarbonyl, or formyl); and X and Y are independently oxygen or sulphur.

  式(I)的杀菌化合物： 其中 A 是氟、氯、溴、碘、C₁₋₄ 烷基、C₁₋₄ 烷氧基、卤代(C₁₋₄)烷基、C₁₋₄ 烷氧基甲基、C₁₋₄ 烷硫基甲基、C₂₋₄烯基、C₂₋₄炔基、C₁₋₄ 烷氧基羰基、C₁₋₄ 烷基羰基、甲酰基、氰基、硝基或 C₁₋₄ 烷硫基；R¹ 和 R² 独立地为 C₁₋₄烷基、C₃₋₆烯基（可选择被卤素取代）、C₃₋₆炔基（可选择被卤素取代） C₁₋₄ 烷氧基、卤代(C₁₋₄)-烷基、C₃₋₆环烷基、C₃₋₆环烷基(C₁₋₄)烷基、C₁₋₄烷氧基(C₁₋₄)-烷基、C₁₋₄烷硫基(C₁₋₄)烷基或氰基，或 R¹ 和 R² 与它们所连接的氮一起形成吗啉、哌啶、吡咯烷或氮杂环，可任选被 C₁₋₄ 烷基取代；R³ 是 H，或 R³ 和 R⁴，连同它们所连接的基团 C(0)N 形成氮杂环丁烷-2-酮环，该环可任选被 C₁₋₄烷基取代；R⁴ 是 C₂₋₈ 烷基、C₂₋₈ 烯基、C₂₋₈ 炔基或 C₃₋₆ 环烷基，所有这些环烷基可任选被卤素、C₁₋₄ 烷基、C₁₋₄ 烷氧基、C₁₋₄ 烷硫基取代、氰基、C₁₋₄ 烷基羰基、C₁₋₄ 烷氧基羰基、叠氮、硝基、异氰基或 NR⁵R⁶（其中 R⁵ 和 R⁶ 独立地为 H、C₁₋₄ 烷基、C₁₋₄ 烷基羰基或甲酰基）；X 和 Y 独立地为氧或硫。