3-Azido-4-(3,5-dichlorophenyl)-4,5-dihydro-1,2-oxazole

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-Azido-4-(3,5-dichlorophenyl)-4,5-dihydro-1,2-oxazole
• 英文别名: 3-azido-4-(3,5-dichlorophenyl)-4,5-dihydro-1,2-oxazole
• 化学式: C9H6Cl2N4O
• 分子量: 257.07
• InChiKey: VJNOYPQQBFVKCZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  36
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Bifunctional heterocyclic compounds and methods of making and using same
  申请人：Wang Deping

  公开号：US20050197334A1

  公开（公告）日：2005-09-08

  The invention provides a family of bifunctional heterocyclic compounds useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. The invention also provides methods of making the bifunctional heterocyclic compounds, and methods of using such compounds as anti-infective, anti-proliferative agents, anti-inflammatory, and/or prokinetic agents.

  本发明提供了一族双功能杂环化合物，可用作抗感染、抗增殖、抗炎症和促动力药物。本发明还提供了制备双功能杂环化合物的方法，以及使用这些化合物作为抗感染、抗增殖剂、抗炎症和/或促动力药物的方法。
• BIFUNCTIONAL HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING SAME
  申请人：Rib-X Pharmaceuticals, Inc.

  公开号：EP1543017A2

  公开（公告）日：2005-06-22
• US7091196B2
  申请人：——

  公开号：US7091196B2

  公开（公告）日：2006-08-15
• US7335753B2
  申请人：——

  公开号：US7335753B2

  公开（公告）日：2008-02-26
• [EN] BIFUNCTIONAL HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING SAME<br/>[FR] COMPOSES HETEROCYCLIQUES BIFONCTIONNELS ET PROCEDES DE FABRICATION ET D'UTILISATION DE CES COMPOSES
  申请人：RIB X PHARMACEUTICALS INC

  公开号：WO2004029066A2

  公开（公告）日：2004-04-08

  The invention provides a family of bifunctional heterocyclic compounds useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. The invention also provides methods of making the bifunctional hetercyclic compounds, and methods of using such compounds as anti-infective, anti-proliferative agents, anti-inflammatory, and/or prokinetic agents.