DC_8,9 phosphatidylethanolamine | 127192-82-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油磷脂
• 英文名称: DC_8,9 phosphatidylethanolamine
• 英文别名: [3-[2-Aminoethoxy(hydroxy)phosphoryl]oxy-2-tricosa-10,12-diynoyloxypropyl] tricosa-10,12-diynoate
• CAS: 127192-82-9
• 化学式: C₅₁H₈₆NO₈P
• 分子量: 872.219
• InChiKey: ZBLCBXGAYXHPIY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  14.1
• 重原子数：
  61
• 可旋转键数：
  45
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  134
• 氢给体数：
  2
• 氢受体数：
  9

反应信息

• 作为产物：
  描述：

  乙醇胺盐酸盐 、 1,2 bis (tricosa 10,12 diynoyl)-sn-3-glycerophosphocholine, DC_8,9PC 在 acetate buffer 作用下， 以 异丙醇 为溶剂， 反应 10.0h， 以10%的产率得到DC_8,9 phosphatidylethanolamine
  参考文献：
  名称：

  Phosphatidylhydroxyalkanols as Versatile Intermediates in the Synthesis of Headgroup Modified Diacetylenic Phospholipids

  摘要：

  Phospholipase D extract (from savoy cabbage) mediates exchange of omega hydroxyalkanols (n= 2-4) with the choline moiety of phosphatidylcholines to produce corresponding phosphatidylhydroxyalkanols in >70% yield. The phosphatidyl hydroxyalkanol and its chloro analogue-were further reacted with molecules containing carboxylic and amine functionality respectively, providing an easy and efficient method to produce headgroup modified phospholipids.

  DOI：

  10.1080/00397919208019084

文献信息

• PROCESS AND DEVICE FOR LARGE-SCALE NONCOVALENT FUNCTIONALIZATION OF NANOMETER-SCALE 2D MATERIALS USING HEATED ROLLER LANGMUIR-SCHAEFER CONVERSION
  申请人：Purdue Research Foundation

  公开号：US20210060604A1

  公开（公告）日：2021-03-04

  The present invention generally relates to a device and a process for performing large-scale noncovalent functionalization of 2D materials, with chemical pattern elements as small as a few nanometers, using thermally controlled rotary Langmuir-Schaefer conversion. In particular, the present invention discloses a device comprising a thermally regulated disc driven by a rotor with fine speed control configured to be operable with a Langmuir trough for performing large-scale noncovalent functionalization of 2D materials, achieving ordered domain areas up to nearly 10,000 μm 2 , with chemical pattern elements as small as a few nanometers. A process using the device for performing large-scale noncovalent functionalization of 2D materials with chemical pattern elements as small as a few nanometers is within the scope of this disclosure. The process we demonstrate would be readily extensible to roll-to-roll processing, addressing a longstanding challenge in scaling Langmuir-Schaefer transfer for practical applications.
• Phosphatidylhydroxyalkanols as Versatile Intermediates in the Synthesis of Headgroup Modified Diacetylenic Phospholipids
  作者：Alok Singh、Michael Markowitz、Li-I Tsao

  DOI：10.1080/00397919208019084

  日期：1992.8

  Phospholipase D extract (from savoy cabbage) mediates exchange of omega hydroxyalkanols (n= 2-4) with the choline moiety of phosphatidylcholines to produce corresponding phosphatidylhydroxyalkanols in >70% yield. The phosphatidyl hydroxyalkanol and its chloro analogue-were further reacted with molecules containing carboxylic and amine functionality respectively, providing an easy and efficient method to produce headgroup modified phospholipids.