[1,7]phenanthrolin-5-ylamine | 41148-67-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 菲咯啉
• 英文名称: [1,7]phenanthrolin-5-ylamine
• 英文别名: 1,7-Phenanthrolin-5-amine
• CAS: 41148-67-8
• 化学式: C₁₂H₉N₃
• 分子量: 195.224
• InChiKey: QGHBJBNEKVWDKS-UHFFFAOYSA-N

物化性质

• 沸点：
  441.1±30.0 °C(Predicted)
• 密度：
  1.333±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  15
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  51.8
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  5-nitro-phenanthroline 在 盐酸 、 tin 、 水 作用下， 生成 [1,7]phenanthrolin-5-ylamine
  参考文献：
  名称：

  DE693090

  摘要：

  公开号：

文献信息

• Luminescent metal-ligand complexes
  申请人：LJL BioSystems, Inc.

  公开号：US20010021514A1

  公开（公告）日：2001-09-13

  Luminescent metal-ligand complexes and/or complementary energy transfer acceptors for use in luminescence assays. The complexes and/or acceptors may be used in free, reactive, and/or conjugated form, alone or mixed with other compounds. Preferred luminescence assays include luminescence polarization and luminescence resonance energy transfer assays, among others.

  荧光金属配合物和/或互补能量转移受体用于荧光测定。这些配合物和/或受体可以以自由、反应性和/或共轭形式使用，单独或与其他化合物混合使用。首选的荧光测定包括荧光偏振和荧光共振能量转移测定，等等。
• Time-resolved fluorimetric detection of lanthanide labeled nucleotides
  申请人：THE PERKIN-ELMER CORPORATION

  公开号：EP0340675A2

  公开（公告）日：1989-11-08

  Nucleotides conjugated with a chelating agent and labeled with a lanthanide, especially terbium, are readily detected by time-resolved fluorimetry during and following gel electrophoresis. The labeled nucleotide conjugates are very stable, highly fluorescent with a long radiative lifetime and remain fluorescent during dilution and during gel electrophoresis and since an enhancement solution is not required for detection, the labeled nucleotide conjugates can be detectd on-line, if desired.

  核苷酸与螯合剂共轭并用镧系元素（尤其是铽元素）标记后，在凝胶电泳过程中和电泳后很容易通过时间分辨荧光测定法进行检测。标记的核苷酸共轭物非常稳定，荧光强度高，辐射寿命长，在稀释过程中和凝胶电泳过程中都能保持荧光，而且由于检测不需要增强溶液，如果需要，标记的核苷酸共轭物可以在线检测。
• Europium beta-diketonate luminescent material
  申请人：Melman Jonathan

  公开号：US11041119B2

  公开（公告）日：2021-06-22

  A Europium beta-diketonate molecule comprises Europium with ligands dibenzoylmethane, 1,10-phenanthroline, and methoxide. The molecule is photoluminescent, absorbing light from the ultraviolet region through the blue region and emitting red light characteristic of trivalent europium. The molecule may be used, for example, as a phosphor in a phosphor-converted light-emitting diode.

  β-二酮酸铕分子由铕与配体二苯甲酰甲烷、1,10-菲罗啉和甲氧基组成。该分子具有光致发光性，可吸收紫外区到蓝光区的光，并发出三价铕特有的红光。例如，该分子可用作荧光转换发光二极管中的荧光粉。
• Compositions and methods for inhibiting platelet activation and thrombosis
  申请人：Beth Israel Deaconess Medical Center

  公开号：US20040147540A1

  公开（公告）日：2004-07-29

  The invention provides methods and compositions for reducing platelet activation, platelet aggregation and thrombosis. The invention further provides compositions and methods for treating or preventing diseases or disorders in which the pathology of the disease or disorder involves one or more of platelet activation, platelet aggregation and thrombus formation. The invention additionally relates to the use of protein palmitoylation inhibitors for the reduction of platelet activation, platelet aggregation and thrombosis, as well as to the use of protein palmitoylation as a target for the identification of inhibitors of platelet activation, platelet aggregation and thrombosis.

  本发明提供了减少血小板活化、血小板聚集和血栓形成的方法和组合物。本发明进一步提供了用于治疗或预防疾病或失调的组合物和方法，其中疾病或失调的病理涉及血小板活化、血小板聚集和血栓形成中的一种或多种。本发明还涉及使用蛋白棕榈酰化抑制剂降低血小板活化、血小板聚集和血栓形成，以及使用蛋白棕榈酰化作为靶点鉴定血小板活化、血小板聚集和血栓形成抑制剂。
• Method for the manufacture of electrode for energy-storage devices
  申请人：Timonov Mikhailovich Alexander

  公开号：US20050217998A1

  公开（公告）日：2005-10-06

  Application of a redox polymer of the poly-[Me(R-Salen)] type onto a conducting substrate is accomplished by the method of electrochemical polymerization. Said polymerization is accomplished by supplying a voltage between the substrate (that serves as an anode) and a counter electrode (that serves as a cathode), with both of them being submerged into the electrolyte containing an organic solvent and the compounds capable of dissolving in said solvent. The process is accompanied by the production of electrochemically inactive (at concentrations of no less than 0.01 mol/l) ions within the range of potentials from −3.0 V to +1.5 V, and metal complex [Me(R-Salen)] dissolved at a concentration of no less than 5·10 −5 mol/l, (where: Me is a transition metal having at least two different degrees of oxidation, R is an electron-donating substituent, Salen is a residue of bis-(salicylaldehyde)-ethylenediamine in Schiff's base.

  将聚[Me(R-Salen)]型氧化还原聚合物应用到导电基底上是通过电化学聚合的方法实现的。聚合的方法是在基底（作为阳极）和反电极（作为阴极）之间施加电压，将二者浸入含有有机溶剂和能溶解于所述溶剂的化合物的电解液中。在这一过程中，会产生电化学不活泼（浓度不低于 0.01 摩尔/升）的离子，其电位范围为 -3.0 V 至 +1.5 V，同时还会产生溶解浓度不低于 5-10 摩尔/升的金属络合物[Me(R-Salen)]。 -5 摩尔/升，（其中Me 是具有至少两种不同氧化度的过渡金属，R 是一个给电子的取代基，Salen 是希夫碱中的双-（水杨醛）-乙二胺残基。