Benzamidin-4-sulfofluorid | 32752-19-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Benzamidin-4-sulfofluorid
• 英文别名: Benzenesulfonyl fluoride, 4-(aminoiminomethyl)-；4-carbamimidoylbenzenesulfonyl fluoride
• CAS: 32752-19-5
• 化学式: C₇H₇FN₂O₂S
• 分子量: 202.209
• InChiKey: LIXKVGAXCBVJLI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  92.4
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Macromolecular enzyme substrates
  申请人：——

  公开号：US20030186345A1

  公开（公告）日：2003-10-02

  The present invention features methods for measuring the activity of an enzyme (such as a proteinase or an endosaccharidase) in a sample, using a macromolecular substrate of the enzyme. Also featured are methods for: detecting the level of peptidase activity of a proteinase; measuring amylase activity in a sample; diagnosing pancreatitis in a subject; measuring the activity of a target isoenzyme in a sample; identifying a compound that modulates the activity of a proteinase or an endosaccharidase; and identifying an antibody that modulates the activity of a proteinase or an endosaccharidase, using the macromolecular substrates provided by the present invention.

  本发明的特点是使用酶的大分子底物测量样品中酶（如蛋白酶或内糖酶）的活性的方法。本发明还包括以下方法：检测蛋白酶的肽酶活性水平；测量样品中淀粉酶的活性；诊断受试者的胰腺炎；测量样品中目标同工酶的活性；利用本发明提供的大分子底物鉴定调节蛋白酶或内糖酶活性的化合物；以及鉴定调节蛋白酶或内糖酶活性的抗体。
• [EN] MACROMOLECULAR ENZYME SUBSTRATES<br/>[FR] SUBSTRATS MACROMOLECULAIRES POUR ENZYMES
  申请人：GOVERNMENT OF UNITED STATES OF

  公开号：WO2002010439A2

  公开（公告）日：2002-02-07

  The present invention features methods for measuring the activity of an enzyme (such as a proteinase or an endosaccharidase) in a sample, using a macromolecular substrate of the enzyme. Also featured are methods for: detecting the level of peptidase activity of a proteinase; measuring amylase activity in a sample; diagnosing pancreatitis in a subject; measuring the activity of a target isoenzyme in a sample; identifying a compound that modulates the activity of a proteinase or an endosaccharidase; and identifying an antibody that modulates the activity of a proteinase or an endosaccharidase, using the macromolecular substrates provided by the present invention.