1,4-Benzenediol, bis(1,1-dimethylethyl)- | 1322-72-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,4-Benzenediol, bis(1,1-dimethylethyl)-
• 英文别名: 2,3-ditert-butylbenzene-1,4-diol
• CAS: 1322-72-1
• 化学式: C₁₄H₂₂O₂
• 分子量: 222.32
• InChiKey: YXGOYRIWPLGGKN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM
  申请人：Whitten Jeffrey P.

  公开号：US20110263612A1

  公开（公告）日：2011-10-27

  Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.

  本文描述了含有这些化合物的化合物和药物组合物，这些化合物调节储存操作钙（SOC）通道的活性。本文还描述了使用这种SOC通道调节剂的方法，单独或与其他化合物结合，用于治疗需要抑制SOC通道活性的疾病或症状。
• [EN] COMPOUND, PHOTOPOLYMERIZATION INITIATOR, PHOTOCURABLE COMPOSITION AND CURED PRODUCT THEREOF, AND PHOTOCURABLE INK AND PRINT USING THE SAME<br/>[FR] COMPOSÉ, INITIATEUR DE PHOTOPOLYMÉRISATION, COMPOSITION PHOTODURCISSABLE ET PRODUIT DURCI ASSOCIÉ, ENCRE PHOTODURCISSABLE ET IMPRESSION L'UTILISANT
  申请人：DAINIPPON INK & CHEMICALS

  公开号：WO2019071428A1

  公开（公告）日：2019-04-18

  There are provided a compound represented by general formula (1), a photopolymerization initiator comprising this compound, a photocurable composition having this photopolymerization initiator and a photocurable compound as essential components, and a cured product formed by curing this photocurable composition, wherein in formula (l), R1 and R2 each independently represents an alkyl group or the like; R3 to R5 each independently represent a hydrogen atom, an alkyl group or the like; X1 represents a single bond or an alkylene group; and X2 represents a bonding group represented by general formulas (2) to (4), and wherein n represents an integer of 1 to 6, when n is an integer of 1, Y represents an alkyl group, an aryl group or the like.

  提供了一个化合物，其通式表示为（1），包括该化合物的光聚合引发剂，具有该光聚合引发剂和光固化化合物作为基本组分的光固化组合物，以及通过固化该光固化组合物形成的固化产物，其中在通式（1）中，R1和R2分别独立表示烷基基团或类似物；R3至R5分别独立表示氢原子、烷基基团或类似物；X1表示单键或烷基烃基团；X2表示由通式（2）至（4）表示的键合基团，其中n表示1至6的整数，当n为1时，Y表示烷基基团、芳基基团或类似物。
• [EN] COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM<br/>[FR] COMPOSÉS QUI MODULENT LE CALCIUM INTRACELLULAIRE
  申请人：CALCIMEDICA INC

  公开号：WO2015054283A1

  公开（公告）日：2015-04-16

  Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store -operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.

  本文描述了含有这些化合物的化合物和药物组合物，这些化合物调节存储 - 操作的钙（SOC）通道的活性。本文还描述了使用这种SOC通道调节剂的方法，单独或与其他化合物结合，用于治疗需要抑制SOC通道活性的疾病或症状。
• [EN] ACRYLATE-FUNCTIONAL BRANCHED ORGANOSILICON COMPOUND, METHOD OF PREPARING SAME, AND COPOLYMER FORMED THEREWITH<br/>[FR] COMPOSÉ D'ORGANOSILICIUM RAMIFIÉ À FONCTION ACRYLATE, SON PROCÉDÉ DE PRÉPARATION ET COPOLYMÈRE FORMÉ AVEC CELUI-CI
  申请人：DOW SILICONES CORP

  公开号：WO2020142474A1

  公开（公告）日：2020-07-09

  A method of preparing an acrylate-functional branched organosilicon compound ("compound") is provided, and comprises reacting (A) a branched organosilicon compound and (B) an acrylate compound in the presence of (C) a catalyst, wherein component (A) has the general formula X-Si(R1)3, where X comprises a halogen-functional moiety and each R1 is selected from R and –OSi(R4)3, with the proviso that at least one R1 is –OSi(R4)3; each R4 is selected from R, –OSi(R5)3, and –[OSiR2]mOSiR3; each R5 is selected from R, –OSi(R6)3, and –[OSiR2]mOSiR3; each R6 is selected from R and –[OSiR2]mOSiR3; each R is an independently selected hydrocarbyl group; and 0≤m≤100; with the proviso that at least one of R4, R5 and R6 is –[OSiR2]mOSiR3. The compound prepared by the method, a copolymer comprising the reaction product of the compound and a second compound, a method of forming the copolymer, and a composition comprising the copolymer are each also provided.

  提供了一种制备丙烯酸酯官能化分支有机硅化合物（“化合物”）的方法，包括在催化剂存在下，使（A）分支有机硅化合物和（B）丙烯酸酯化合物发生反应，其中组分（A）具有一般式X-Si（R1）3，其中X包括卤素官能基，每个R1从R和–OSi（R4）3中选择，但至少一个R1为–OSi（R4）3；每个R4从R、–OSi（R5）3和–[OSiR2]mOSiR3中选择；每个R5从R、–OSi（R6）3和–[OSiR2]mOSiR3中选择；每个R6从R和–[OSiR2]mOSiR3中选择；每个R是独立选择的烃基；且0≤m≤100；但至少一个R4、R5和R6为–[OSiR2]mOSiR3。还提供了通过该方法制备的化合物，包括化合物和第二化合物的反应产物的共聚物，形成共聚物的方法，以及包含共聚物的组合物。
• Olefin polymerization catalyst system and process for use thereof
  申请人：Rix C. Francis

  公开号：US20060009595A1

  公开（公告）日：2006-01-12

  This invention relates to a compound represented by the formula: where M is a transition metal selected from group 4 of the periodic table; each R 1 is independently selected from the group consisting of hydrogen, hydrocarbyl, substituted hydrocarbyl and functional group, and any two R 1 may be linked, provided that if the two R 1 groups are linked, then they do not form a butadiene group when M is Zr; each R 2 is independently selected from the group consisting of methyl, ethyl, propyl, butyl, pentyl, hexyl and the isomers thereof, provided that when R 3 and R 6 and or R 12 and R 15 form a 5 carbon ring, then each R 2 is independently selected from the group consisting of ethyl, propyl, butyl, pentyl, hexyl and the isomers thereof; R 3 is carbon or silicon; R 4 is hydrogen, hydrocarbyl, substituted hydrocarbyl or a functional group; a is 0, 1, or 2; R 5 is hydrogen, hydrocarbyl, substituted hydrocarbyl or a functional group, R 4 and R 5 may be bound together to form a ring, and R 5 and R 3 may be bound together to form a ring; b is 0, 1, or 2; R 6 is carbon or silicon; and R 4 and R 6 may be bound together to form a ring; each R 7 is hydrogen; each R 8 is independently selected from the group consisting of hydrogen, methyl, ethyl, propyl, butyl, pentyl, hexyl and the isomers thereof; each R 9 is independently selected from the group consisting of hydrogen, hydrocarbyl, substituted hydrocarbyl and a functional group, and two R 9 groups may be linked together to form a ring, R 9 and R 8 may be linked together to form a ring, R 9 and R 16 may be linked together to form a ring, R 9 and R 11 may be linked together to form a ring; c is 0, 1 or 2; R 10 is -M 2 (R 16 ) h — where M 2 is B, Al, N, P, Si or Ge, h is an integer from 1 to 2 , such that the valence of M 2 is filled, and R 16 is hydrogen, hydrocarbyl, substituted hydrocarbyl or a functional group, and two R 16 groups may be linked together to form a ring; d is 0, 1, or 2; each R 11 is independently selected from the group consisting of hydrogen, hydrocarbyl, substituted hydrocarbyl and a functional group, and two R 11 groups may be linked together to form a ring. R 11 and R 8 may be linked together to form a ring. R 11 and R 16 may be linked together to form a ring; e is 0, 1, or 2; where the sum of c, d, and e is 1, 2 or 3; R 12 is carbon or silicon; R 13 is hydrogen, hydrocarbyl, substituted hydrocarbyl or a functional group, and R 13 and R 14 may be bound together to form a ring, and R 13 and R 15 may be bound together to form a ring, when g is 0; f is 0, 1, or 2; R 14 is hydrogen, hydrocarbyl, substituted hydrocarbyl or a functional group, and R 14 and R 12 may be bound together to form a ring, when f is 0; g is 0, 1, or 2; and R 15 is carbon or silicon. This invention further relates to a process to polymerize unsaturated monomers using the above compositions.

  本发明涉及一种由以下公式表示的化合物：其中M是周期表中4族过渡金属中选取的元素；每个R1独立地选自氢、烃基、取代烃基和官能团组成的群体，任意两个R1可能被连接，前提是如果两个R1组被连接，则当M为Zr时它们不形成丁二烯基团；每个R2独立地选自甲基、乙基、丙基、丁基、戊基、己基及其异构体组成的群体，前提是当R3和R6以及/或R12和R15形成一个5碳环时，每个R2独立地选自乙基、丙基、丁基、戊基、己基及其异构体；R3是碳或硅；R4是氢、烃基、取代烃基或官能团；a为0、1或2；R5是氢、烃基、取代烃基或官能团，R4和R5可能结合形成一个环，R5和R3可能结合形成一个环；b为0、1或2；R6是碳或硅；R4和R6可能结合形成一个环；每个R7是氢；每个R8独立地选自氢、甲基、乙基、丙基、丁基、戊基、己基及其异构体；每个R9独立地选自氢、烃基、取代烃基和官能团组成的群体，两个R9组可能连接以形成一个环，R9和R8可能连接以形成一个环，R9和R16可能连接以形成一个环，R9和R11可能连接以形成一个环；c为0、1或2；R10是-M2(R16)h—，其中M2是B、Al、N、P、Si或Ge，h是1到2之间的整数，使得M2的价被填满，R16是氢、烃基、取代烃基或官能团，两个R16组可能连接以形成一个环；d为0、1或2；每个R11独立地选自氢、烃基、取代烃基和官能团组成的群体，两个R11组可能连接以形成一个环。R11和R8可能连接以形成一个环。R11和R16可能连接以形成一个环；e为0、1或2；其中c、d和e的总和为1、2或3；R12是碳或硅；R13是氢、烃基、取代烃基或官能团，当g为0时，R13和R14可能结合形成一个环，R13和R15可能结合形成一个环；f为0、1或2；R14是氢、烃基、取代烃基或官能团，当f为0时，R14和R12可能结合形成一个环；g为0、1或2；R15是碳或硅。此外，本发明还涉及使用上述组合物聚合不饱和单体的方法。