2,3-dihydro-1H-pyrazolo[3,4-c]pyridine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2,3-dihydro-1H-pyrazolo[3,4-c]pyridine
• 化学式: C₆H₇N₃
• 分子量: 121.14
• InChiKey: MZJQMKPCBUFKCE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  9
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  37
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• COMPOSITIONS AND METHODS FOR TREATING CNS DISORDERS
  申请人：Sage Therapeutics, Inc.

  公开号：US20170240589A1

  公开（公告）日：2017-08-24

  Described herein are neuroactive steroids of the Formula (I): or a pharmaceutically acceptable salt thereof; wherein (II), A, R 1 , R 2 , R 3a , R 4a , R 4b , R 5 , R 7a , and R 7b are as defined herein. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. The present invention also provides pharmaceutical compositions comprising a compound of the present invention and methods of use and treatment, e.g., such for inducing sedation and/or anesthesia.