1,6-Diazacycloundecan-2-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酰胺类
• 英文名称: 1,6-Diazacycloundecan-2-one
• 英文别名: 1,6-diazacycloundecan-2-one
• 化学式: C₉H₁₈N₂O
• 分子量: 170.25
• InChiKey: USHFNZGJECXBHX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  41.1
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF
  申请人：Aptinyx Inc.

  公开号：US20210047324A1

  公开（公告）日：2021-02-18

  Disclosed are compounds having potency in the modulation of NMDA receptor activity. Such compounds can be useful in the treatment of conditions such as depression and related disorders as well as other disorders.
• [EN] SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF<br/>[FR] MODULATEURS DES RÉCEPTEURS NMDA SPIRO-LACTAMES ET LEURS UTILISATIONS
  申请人：APTINYX INC

  公开号：WO2019152678A1

  公开（公告）日：2019-08-08

  Disclosed are compounds having potency in the modulation of NMDA receptor activity. Such compounds can be useful in the treatment of conditions such as depression and related disorders as well as other disorders.