1-Hydroxy-2,6-dimethylpyridin-1-ium

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 1-Hydroxy-2,6-dimethylpyridin-1-ium
• 化学式: C₇H₁₀NO
• 分子量: 124.162
• InChiKey: PDMPOIQLSLBSSI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  9
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  24.1
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• 5- AND 6-MEMBERED HETEROCYCLIC COMPOUNDS
  申请人：EnVivo Pharmaceuticals, Inc.

  公开号：US20140038965A1

  公开（公告）日：2014-02-06

  5- and 6-membered heterocyclic compounds which are inhibitors of phosphodiesterase 10 are described as are processes, pharmaceutical compositions, pharmaceutical preparations and pharmaceutical use of the compounds in the treatment of mammals, including human(s) for central nervous system (CNS) disorders and other disorders which may affect CNS function. Also described is the treatment of neurological, neurodegenerative and psychiatric disorders including but not limited to those comparing cognitive deficits or schizophrenic symptoms.

  本文描述了5-和6-成员杂环化合物，它们是磷酸二酯酶10的抑制剂，以及这些化合物在治疗哺乳动物（包括人类）的中枢神经系统（CNS）疾病和其他可能影响CNS功能的疾病中的过程、制药组合物、制药制剂和制药用途。还描述了治疗神经、神经退行性和精神障碍，包括但不限于那些比较认知缺陷或精神分裂症状的方法。
• ADMINISTRATION REGIME FOR NITROCATECHOLS
  申请人：Bial-Portela & CA, S.A.

  公开号：EP2307020B1

  公开（公告）日：2019-02-20
• [EN] OXIDIZED POLYISOBUTENE COMPOUNDS AND METHODS OF MAKING THE SAME<br/>[FR] COMPOSÉS DE POLYISOBUTÈNE OXYDÉ ET LEURS PROCÉDÉS DE PRÉPARATION
  申请人：UNIV CALIFORNIA

  公开号：WO2021222630A1

  公开（公告）日：2021-11-04

  Disclosed herein, inter alia, are oxidized polyisobutene compounds and compositions and methods of making the same.
• [EN] OXIDIZED POLYETHYLENE COMPOUNDS AND METHODS OF MAKING THE SAME<br/>[FR] COMPOSÉS DE POLYETHYLЀNE OXYDÉ ET LEURS PROCÉDÉS DE FABRICATION
  申请人：UNIV CALIFORNIA

  公开号：WO2021222634A1

  公开（公告）日：2021-11-04

  Disclosed herein, inter alia, are oxidized polyethylene compounds and compositions and methods of making the same.