2-acetyl-N-(2-pyrrolidin-1-ylethyl)cyclohexane-1-carboxamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: 2-acetyl-N-(2-pyrrolidin-1-ylethyl)cyclohexane-1-carboxamide
• 化学式: C₁₅H₂₆N₂O₂
• 分子量: 266.38
• InChiKey: MUYVXCLQZXWLDF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  19
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.87
• 拓扑面积：
  49.4
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• RELEASABLE CONJUGATES
  申请人：QuiaPEG Pharmaceuticals AB

  公开号：EP4011396A1

  公开（公告）日：2022-06-15

  The present application provides compounds of Formula (B): or pharmaceutically acceptable salts thereof, wherein D is a residue of a biologically active drug, which underdo hydrolysis under physiological conditions to release the biologically active drug and which are useful in the treatment of disorders that could be beneficially treated with the drug.

  本申请提供了式 (B) 的化合物： 或其药学上可接受的盐，其中 D 是生物活性药物的残留物，在生理条件下可水解释放出生物活性药物，可用于治疗可使用该药物进行有益治疗的疾病。
• [EN] RELEASABLE GLP-1 CONJUGATES<br/>[FR] CONJUGUÉS DE GLP-1 LIBÉRABLES
  申请人：QUIAPEG PHARMACEUTICALS AB

  公开号：WO2020053815A1

  公开（公告）日：2020-03-19

  The present application provides compounds of Formula (I), or pharmaceutically acceptable salts thereof, wherein D is a residue of a GLP-polypeptide or an analog thereof, which underdo hydrolysis under physiological conditions to release the GLP-polypeptide or analog thereof and which are useful in the treatment of disorders that could be beneficially treated with the GLP-polypeptide or analog thereof.