OXA 06 dihydrochloride

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: OXA 06 dihydrochloride
• 英文别名: N-[(2-fluorophenyl)methyl]-1-[4-(1H-pyrrolo[2,3-b]pyridin-4-yl)phenyl]methanamine;dihydrochloride
• 化学式: C21H20Cl2FN3
• 分子量: 404.3
• InChiKey: ZRBCUSMZOWMVJS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.5
• 重原子数：
  27
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  40.7
• 氢给体数：
  4
• 氢受体数：
  3

文献信息

• MEDIUM FOR DIRECT DIFFERENTIATION OF PLURIPOTENT STEM CELL-DERIVED MESENCHYMAL STEM CELL, METHOD FOR PREPARING MESENCHYMAL STEM CELL BY USING SAME, AND MESENCHYMAL STEM CELL PREPARED THEREBY
  申请人：CHA Biotech Co., Ltd.

  公开号：EP3848455A1

  公开（公告）日：2021-07-14

  The present invention relates to a medium for direct differentiation of embryonic stem cell-derived mesenchymal stem cells, a method of preparing mesenchymal stem cells by using same, mesenchymal stem cells prepared thereby, and a cell therapy product comprising the same mesenchymal stem cells. In a medium composition and a method according to an embodiment, mesenchymal stem cells may be prepared at high yield within a short period of time. In addition, the method is simple in preparation procedure because of the absence of an embryoid body formation step and allows homogeneous cells to be prepared, thus advantageously providing a cell therapy product within a reduce period of time, compared to conventional methods.

  本发明涉及一种用于直接分化胚胎干细胞衍生间充质干细胞的培养基、使用该培养基制备间充质干细胞的方法、由此制备的间充质干细胞以及包含相同间充质干细胞的细胞治疗产品。根据一个实施方案中的培养基组合物和方法，间充质干细胞可在短时间内高产制备。此外，由于没有胚状体形成步骤，该方法制备程序简单，可制备均质细胞，因此与传统方法相比，可在较短时间内提供细胞治疗产品。