Dithiobenzoesaeure-isopropylester | 5925-56-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Dithiobenzoesaeure-isopropylester
• 英文别名: 1-Methylethyldithiobenzoate；propan-2-yl benzenecarbodithioate
• CAS: 5925-56-4
• 化学式: C₁₀H₁₂S₂
• 分子量: 196.337
• InChiKey: XEVWHEPHOAYGEZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  57.4
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  Dithiobenzoesaeure-isopropylester 、 碘甲烷 在 高氯酸四乙基铵 作用下， 生成 Isopropylthio(methylthio)phenylmethan
  参考文献：
  名称：

  Kistenbruegger, Lothar; Voss, Juergen, Liebigs Annalen der Chemie, 1980, # 3, p. 472 - 480

  摘要：

  DOI：
• 作为产物：
  描述：

  N,N-二甲基苯甲酰胺 、 二硫代磷酸-O,O-二(1-甲基乙基)酯 生成 Dithiobenzoesaeure-isopropylester
  参考文献：
  名称：

  Perregaard,J. et al., Bulletin des Societes Chimiques Belges, 1977, vol. 86, p. 321 - 328

  摘要：

  DOI：

文献信息

• Preparation of dithioesters by ester interchange and the PMR spectral properties of these compounds
  作者：N.H. Leon、R.S. Asquith

  DOI：10.1016/s0040-4020(01)93022-4

  日期：1970.1

  Aromatic and aliphatic dithioesters, many of them new, have been easily synthesized in excellent yields by the ester interchange reaction between carboxymethyl dithioesters and mercaptans. PMR spectra of these dithioesters and the corresponding oxygen analogues show that a strong anisotropic deshielding effect is associated with the highly polarized thiocarbonyl group.

  通过羧甲基二硫代酯与硫醇的酯交换反应，可以容易地以优异的产率合成芳族和脂肪族二硫代酯，其中许多是新的。这些二硫代酸酯和相应的氧类似物的PMR光谱表明，强极化的各向异性屏蔽作用与高度极化的硫代羰基有关。
• ISOSORBIDE-BASED POLYMETHACRYLATES
  申请人：Hillmyer Marc A.

  公开号：US20160229863A1

  公开（公告）日：2016-08-11

  A monomer comprises the structure wherein R 1 comprises H or a substituted hydrocarbyl or unsubstituted hydrocarbyl, and wherein R 2 comprises H, a halide, or a substituted or unsubstituted (C 1 -C 4 ) hydrocarbyl. A method comprises (a) reacting a dianhydrohexitol precursor having the structure with an acyl-group containing compound having the structure wherein R 1 comprises H or a substituted hydrocarbyl or unsubstituted hydrocarbyl, and X comprises a halide, a hydroxyl group, or an acyl group to form an acylated dianhydrohexitol ester intermediate having the structure and (b) reacting the acylated dianhydrohexitol ester intermediate with an acrylic-based compound having the structure wherein R 2 comprises H, a halide, or a substituted or unsubstituted (C 1 -C 4 ) hydrocarbyl, and Y comprises a halide, a hydroxyl group, or an acyl group, to form a dianhydrohexitol-based monomer having the structure

  一个单体包括结构，其中R1包括H或取代的烃基或未取代的烃基，R2包括H，卤素，或取代或未取代的（C1-C4）烃基。一种方法包括（a）将具有结构的二酮六醇前体与具有结构的含酰基化合物反应，其中R1包括H或取代的烃基或未取代的烃基，X包括卤素，羟基，或酰基，形成具有结构的酰化二酮六醇酯中间体，和（b）将酰化二酮六醇酯中间体与具有结构的丙烯基化合物反应，其中R2包括H，卤素，或取代或未取代的（C1-C4）烃基，Y包括卤素，羟基，或酰基，形成具有结构的二酮六醇基单体。
• Compositions and methods for inducing immune tolerance
  申请人：The University of Chicago

  公开号：US11253579B2

  公开（公告）日：2022-02-22

  Several embodiments provided in the present disclosure relate to compositions that carry an antigen to which tolerance is desired, the antigen being coupled, bound, or otherwise joined to a targeting moiety, the targeting moiety configured to direct the composition to the liver of a subject. In several embodiments, the antigen in coupled to the targeting moiety by way of a polymeric linker. In several embodiments, the polymeric linker is configured to liberate the antigen in vivo. Methods of using the compositions to reduce and/or prevent unwanted immune responses against an antigen of interest are also provided.

  本公开提供的几个实施方案涉及携带抗原的组合物，抗原与靶向分子偶联、结合或以其他方式连接，靶向分子被配置为将组合物导向受试者的肝脏。在几个实施方案中，抗原通过聚合连接体与靶向分子连接。在几个实施方案中，聚合连接体被配置为在体内释放抗原。此外，还提供了使用组合物减少和/或预防针对相关抗原的不必要免疫反应的方法。
• Block copolymer, preparation method thereof, and thin film structure comprising the same
  申请人：INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

  公开号：US11319434B2

  公开（公告）日：2022-05-03

  A block copolymer is provided. The block copolymer includes a first block including repeat units represented by formula (I), and a second block connected to the first block and including repeat units represented by formula (II) or (III). The disclosure also provides a method for preparing the block copolymer and a thin film structure including the same.

  提供一种嵌段共聚物。该嵌段共聚物包括第一嵌段（其中包括由式（I）表示的重复单元）和与第一嵌段相连的第二嵌段（其中包括由式（II）或（III）表示的重复单元）。本公开还提供了一种制备该嵌段共聚物的方法以及包括该嵌段共聚物的薄膜结构。
• Mayer,R. et al., Chemische Berichte, 1966, vol. 99, p. 1393 - 1413
  作者：Mayer,R. et al.

  DOI：——

  日期：——