alpha-[2-[Bis(2-pyridyl)methylene]hydrazono]-2-pyridinemethanol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: alpha-[2-[Bis(2-pyridyl)methylene]hydrazono]-2-pyridinemethanol
• 英文别名: N-(dipyridin-2-ylmethylideneamino)pyridine-2-carboxamide
• 化学式: C₁₇H₁₃N₅O
• 分子量: 303.32
• InChiKey: QFUVMEGEHMVCHT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  80.1
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  2-吡啶甲酰肼 、 2-二吡啶基酮 以 乙醇 为溶剂， 反应 10.0h， 以83%的产率得到alpha-[2-[Bis(2-pyridyl)methylene]hydrazono]-2-pyridinemethanol
  参考文献：
  名称：

  具有桥联（N–N）二嗪配体的三核铜（II）配合物：结构和磁性研究

  摘要：

  多主题 配体2poap和po2p具有线性排列的配位腔，适合于紧密结合金属离子并生成线性三核铜（II）配合物。配合物[Cu 3（2poap-2H）（CH 3 CO 2）4 ]·3H 2 O（1），[Cu 3（2poap-2H）（H 2 O）（DMF ）3（CH 3 OH）2 ] （BF 4）4（2）和[Cu 3（po2p-H）2（H 2 O）2 ]（ClO 4）4 ·2H 2 O（ 3）具有通过N–N单键的反式排列连接的Cu（ II）中心线性排列。每种金属都被指定为ad x 2  -  y 2 磁性基态，反之 二嗪 桥接结构导致强烈的反铁磁耦合，这与以前的磁性结构相关性完全一致，前者将围绕N–N键的铜磁性平面的扭曲与交换积分相关。

  DOI：

  10.1039/b008768h

文献信息

• Synthesis, Structure, and Magnetism of a Series of Self-Assembled Polynuclear Mn(II), Co(II), and Cu(II) Cluster Complexes
  作者：Laurence K. Thompson、Craig J. Matthews、Liang Zhao、Zhiqiang Xu、David O. Miller、Claire Wilson、Michael A. Leech、Judith A.K. Howard、Sarah L. Heath、A.Gavin Whittaker、Richard E.P. Winpenny

  DOI：10.1006/jssc.2001.9160

  日期：2001.7

  monoclinic, C2/c, a=21.7120(4) Å, b=17.421(4) Å, c=17.273(4) Å, β=109.34(3)°. [Co4(poap-H)2(poap-2H)2](NO3)4·7H2O (3); triclinic, P, a=9.6855(6) Å, b=12.9462(7) Å, c=13.7383(8) Å, α=106.5730(10), β=99.0400(10) Å, γ=95.737(10)°. [Co4(poapz-H)4(H2O)4](NO3)4·2H2O (4); monoclinic, C2/c, a=21.160(2) Å, 17.808(2) Å, c=17.000(2) Å, β=106.904(9)°. [Co4(pzoapz-H)4(H2O)4](ClO4)4·3H2O (5); monoclinic, P21/a, a=23.24(1)

  Mn（II），Co（II），Co（II）/ Co（III）和Cu（II）以及一组烷氧基的一系列自组装簇络合物的单晶结构和磁性据报道具有方形和矩形一级结构的二嗪配体。在一种新颖的情况下，由于存在空的核外配位位点，可以在方形核上建立金属离子的二级配位球。[Mn 4（poapz-H）4（H 2 O）4 ]（NO 3）4 ·H 2 O（1）; 单斜，C 2 / c，a = 21.7120（4）Å，b = 17.421（4）Å，c = 17.273（4）Å，β= 109.34（3）°。[Co 4（poap-H）2（poap-2H）2 ]（NO 3）4 ·7H 2 O（3）; 三斜晶，P，a = 9.6855（6）Å，b = 12.9462（7）Å，c = 13.7383（8）Å，α = 106.5730（10），β = 99.0400（10）Å，γ = 95.737（10）° 。[Co 4（poapz-H）4（H
• Synthesis and antibacterial studies of rhodium and iridium complexes comprising of dipyridyl hydrazones
  作者：Basava Punna Rao Aradhyula、Nidhi Joshi、Krishna Mohan Poluri、Mohan Rao Kollipara

  DOI：10.1016/j.molstruc.2018.03.058

  日期：2018.7

  ( 11 ) and Ir ( 12 )} which resulted in a series of mono- and di-nuclear cationic complexes. The complexes have been characterized by various spectroscopic techniques. The solid-state structures of three complexes (5, 6 and 8) have been determined by single-crystal X-ray diffraction studies. These cationic complexes have been evaluated for the preliminary antibacterial activity towards four bacterial

  摘要 Cp*Rh 和 Cp*Ir 二聚体与二吡啶基腙，如吡啶甲酸 (L1)、烟碱 (L2) 和异烟碱 (L3) 的反应已在此处报道，配方 [Cp*MCl L3 ](PF 6 ) 其中M = Rh ( 5 ) 和 Ir ( 6 )}, [(Cp*MCl) 2 L1 ](PF 6 ) 其中 M = Rh ( 7 ) 和 Ir ( 8 )}, [(Cp*MCl) 2 L2 Cl ](PF 6 ) 其中 M = Rh( 9 ) 和 Ir( 10 )}，和 [(Cp*MCl) 2 L3 Cl](PF 6 ) 其中 M = Rh ( 11 ) 和 Ir ( 12 )} 其中导致一系列单核和双核阳离子配合物。这些配合物已通过各种光谱技术表征。三种配合物（5、6 和 8）的固态结构已通过单晶 X 射线衍射研究确定。已经评估了这些阳离子复合物对四种细菌菌株的初步抗菌活性，即金黄色葡萄球菌；苏云金芽孢
• Synthesis, structural, DFT studies and antibacterial evaluation of Cp∗ rhodium and Cp∗ iridium complexes using hydrazide based dipyridyl ketone ligand
  作者：A. Basava Punna Rao、Narasinga Rao Palepu、Debojit Kumar Deb、A. Uma、T. Chiranjeevi、Biplab Sarkar、Werner Kaminsky、Kollipara Mohan Rao

  DOI：10.1016/j.ica.2015.12.035

  日期：2016.3

  The synthesis, characterization and antibacterial evaluation of four new water soluble half-sandwich complexes of N'-di(pyridin-2-yl) methylene}picolinohydrazide (PHADPK-L1) and N'-di(pyridin-2-yl) methylene} nicotinohydrazide (NHADPK-L2) have been described with the general formula [Cp*MLCl] BF4 where L = L1, M = Rh (1), Ir (2); L = L2, M = Rh (3), Ir (4) have been described. All the complexes have been characterized by elemental analysis and spectral studies. Crystal structures of all the complexes 1-4 have been determined by single crystal X-ray analyses. Preliminary in vitro antibacterial activity of the four complexes was investigated against Gram-positive bacterium Staphylococcus aureus, and Gram-negative bacteria viz., Escherichia coli, Klebsiella pneumonia and Pseuedomonas aeruginosa by agar well diffusion method. Spectral and structural studies revealed that the formation of mononuclear complexes takes place by dipyridyl mediated N-N binding. All the complexes exhibited a HOMO (highest occupied molecular orbital)-LUMO (lowest unoccupied molecular orbital) energy gap from 3.65 to 3.97 eV. (C) 2016 Elsevier B.V. All rights reserved.
• USE OF METAL COMPLEX COMPOUNDS AS OXIDATION CATALYSTS
  申请人：Wagner Barbara

  公开号：US20110021407A1

  公开（公告）日：2011-01-27

  The present invention relates to the use of metal complex compounds having hydrazide ligands as oxidation catalysts. Further aspects of the invention are formulations comprising such metal complex compounds, novel metal complex compounds and novel ligands. The metal complex compounds are used especially for enhancing the action of peroxides, for example in the treatment of textile material, without at the same time causing any appreciable damage to fibres and dyeings. There is also no appreciable damage to fibres and dyeings if these metal complexes are used in combination with an enzyme or a mixture of enzymes.
• US7928049B2
  申请人：——

  公开号：US7928049B2

  公开（公告）日：2011-04-19