5,5-dimethyl-3,7-dioxanonane-1,9-diol ditosylate | 92144-78-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 5,5-dimethyl-3,7-dioxanonane-1,9-diol ditosylate
• 英文别名: 2-[2,2-Dimethyl-3-[2-(4-methylphenyl)sulfonyloxyethoxy]propoxy]ethyl 4-methylbenzenesulfonate
• CAS: 92144-78-0
• 化学式: C₂₃H₃₂O₈S₂
• 分子量: 500.634
• InChiKey: CCHDHDMMXYJLFC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  33
• 可旋转键数：
  14
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.48
• 拓扑面积：
  122
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  2-十二烷基-2-甲基丙烷-1,3-二醇 、 5,5-dimethyl-3,7-dioxanonane-1,9-diol ditosylate 在 lithium perchlorate 、 sodium hydride 作用下， 生成 6-dodecyl-6,13,13-trimethyl-1,4,8,11-tetraoxacyclotetradecane
  参考文献：
  名称：

  作为锂离子载体的亲脂性冠 4 衍生物

  摘要：

  准备 de 派生 de composes Crown-4 a cycle de 13 a 16 membres, en vue d'obtenir des ionophores selectifs du 锂。Les mesures potentiometriques montrent que c'est les composes 14-crown-4 et 15-crown-4 qui possedent les meilleurs proprietes

  DOI：

  10.1021/ja00335a019

文献信息

• Macrocyclic receptors containing sucrose skeleton
  作者：Sławomir Jarosz、Arkadiusz Listkowski、Bartosz Lewandowski、Zbigniew Ciunik、Anna Brzuszkiewicz

  DOI：10.1016/j.tet.2005.06.046

  日期：2005.8

  Crown ether analogues with incorporated sucrose unit were prepared by reaction of 1 ',2,3,3 ',4,4 '- hexa-O-benzylsucrose with polyethylene ditosylates in up to 52% yield. Stability constants of their complexes with Li+, Na+, K+, NH4+ were determined by the NMR titration method. The macrocycles were also tested as catalysts in the enantioselective Michael reaction, but with little success (ee up to only 22%). The macrocycle containing nitrogen in the ring was also prepared in good yield. All prepared macrocycles were easily converted into the free sucrose crowns (H-2/Pd/C) without destroying the (very labile) glycosidic bond. The crystal structure of the selected receptor was determined. (c) 2005 Elsevier Ltd. All rights reserved.
• KITAZAWA, SADAYA;KIMURA, KEIICHI;YANO, HIDEKI;SHONO, TOSHIYUKI, J. AMER. CHEM. SOC., 1984, 106, N 23, 6978-6983
  作者：KITAZAWA, SADAYA、KIMURA, KEIICHI、YANO, HIDEKI、SHONO, TOSHIYUKI

  DOI：——

  日期：——
• Lipophilic crown-4 derivatives as lithium ionophores
  作者：Sadaya Kitazawa、Keiichi Kimura、Hideki Yano、Toshiyuki Shono

  DOI：10.1021/ja00335a019

  日期：1984.11

  Preparation de derives de composes crown-4 a cycles de 13 a 16 membres, en vue d'obtenir des ionophores selectifs du lithium. Les mesures potentiometriques montrent que c'est les composes 14-crown-4 et 15-crown-4 qui possedent les meilleurs proprietes

  准备 de 派生 de composes Crown-4 a cycle de 13 a 16 membres, en vue d'obtenir des ionophores selectifs du 锂。Les mesures potentiometriques montrent que c'est les composes 14-crown-4 et 15-crown-4 qui possedent les meilleurs proprietes