N-(4-Hydroxy-phenyl)-thiocarbamidsaeure-O-phenylester | 92903-52-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(4-Hydroxy-phenyl)-thiocarbamidsaeure-O-phenylester
• 英文别名: O-phenyl N-(4-hydroxyphenyl)carbamothioate
• CAS: 92903-52-1
• 化学式: C₁₃H₁₁NO₂S
• 分子量: 245.302
• InChiKey: HCKLZLNOFPFDOS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  73.6
• 氢给体数：
  2
• 氢受体数：
  3

安全信息

• 海关编码：
  2930909090

反应信息

• 作为产物：
  描述：

  对氨基苯酚 、 硫代氯甲酸苯酯 以 1,4-二氧六环 为溶剂， 反应 3.0h， 以69%的产率得到N-(4-Hydroxy-phenyl)-thiocarbamidsaeure-O-phenylester
  参考文献：
  名称：

  Fungicidal activity of phenyl N-(4-substituted-phenyl)thionocarbamates.

  摘要：

  Thirteen phenyl N-(4-substituted-phenyl)thionocarbamates [(4-X-C6H4)NHC(S)OC6H5] were synthesized, and their activities as spore germination inhibitors of Alternaria brassicicola, Botrytis cinerea, Septoria nodorum, and Uromyces viciae-fabae and as protectants against Puccinia recondita on wheat seedlings were determined. High fungicidal activity was found in thionocarbamates substituted with electron-withdrawing groups or the OH group. Results are discussed on the basis of the physicochemical properties of the thionocarbamates.

  DOI：

  10.1021/jf00056a054

文献信息

• MARTIN; WEUFFEN, Pharmazie, 1963, vol. 18, p. 544 - 549
  作者：MARTIN、WEUFFEN

  DOI：——

  日期：——