[(Z)-(16-oxo-oxacyclohexadec-5-ylidene)amino] 2-(2,3-dimethylphenoxy)propanoate | 1107603-90-6

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 大环内酯类和类似物
• 英文名称: [(Z)-(16-oxo-oxacyclohexadec-5-ylidene)amino] 2-(2,3-dimethylphenoxy)propanoate
• CAS: 1107603-90-6
• 化学式: C₂₆H₃₉NO₅
• 分子量: 445.599
• InChiKey: ZVOMOPDMDAIREY-VYIQYICTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7
• 重原子数：
  32
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.65
• 拓扑面积：
  74.2
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  13-羟基亚胺-1-氧杂环十六烷-2-酮 、 2-(2,3-二甲基苯氧基)丙酸 在 N,N'-二环己基碳二亚胺 作用下， 以 二氯甲烷 为溶剂， 反应 12.0h， 生成 [(Z)-(16-oxo-oxacyclohexadec-5-ylidene)amino] 2-(2,3-dimethylphenoxy)propanoate 、 [(E)-(16-oxo-oxacyclohexadec-5-ylidene)amino] 2-(2,3-dimethylphenoxy)propanoate
  参考文献：
  名称：

  Synthesis and Herbicidal Activity of 12-(Aryloxyacyloxyimino)-1,15-pentadecanlactone Derivatives

  摘要：

  A series of novel 12-(aryloxyacyloxyimino)-1, 15-pentadecanlactone derivatives (3) were synthesized, and their structures including configuration of C=N bond were confirmed by H-1 NMR, elemental analysis and X-ray diffraction analysis. The bioassay showed that some of them exhibited excellent herbicidal activity against Amaranthus tricolor L. The activity of compounds 3 except compounds 3A1-2 was much higher than the commercial herbicide 2,4-D and the activity of about half of compounds 3 was comparable to the commercial herbicide tribenuron-methyl. The further bioassay showed that the representative of compounds 3, 3A1-12, exhibited excellent herbicidal activity not only against dicotyledon, such as Amaranthus tricolor L., Cucumis sativus L., Glycine max L., and Phaseolus radiatus L., but also against monocotyledon, such as Zea mays L. and Oryza sativa L.

  DOI：

  10.1021/jf802649w

文献信息

• Synthesis and Herbicidal Activity of 12-(Aryloxyacyloxyimino)-1,15-pentadecanlactone Derivatives
  作者：Xiang-Qing Meng、Jian-Jun Zhang、Xiao-Mei Liang、Wei-Juan Zhu、Yan-Hong Dong、Xue-Min Wu、Jia-Xing Huang、Chang-Hui Rui、Xian-Lin Fan、Fu-Heng Chen、Dao-Quan Wang

  DOI：10.1021/jf802649w

  日期：2009.1.28

  A series of novel 12-(aryloxyacyloxyimino)-1, 15-pentadecanlactone derivatives (3) were synthesized, and their structures including configuration of C=N bond were confirmed by H-1 NMR, elemental analysis and X-ray diffraction analysis. The bioassay showed that some of them exhibited excellent herbicidal activity against Amaranthus tricolor L. The activity of compounds 3 except compounds 3A1-2 was much higher than the commercial herbicide 2,4-D and the activity of about half of compounds 3 was comparable to the commercial herbicide tribenuron-methyl. The further bioassay showed that the representative of compounds 3, 3A1-12, exhibited excellent herbicidal activity not only against dicotyledon, such as Amaranthus tricolor L., Cucumis sativus L., Glycine max L., and Phaseolus radiatus L., but also against monocotyledon, such as Zea mays L. and Oryza sativa L.