Methyl 3-[(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)amino]benzoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Methyl 3-[(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)amino]benzoate
• 英文别名: methyl 3-[(2,4-dioxo-1H-pyrimidin-6-yl)amino]benzoate
• 化学式: C₁₂H₁₁N₃O₄
• 分子量: 261.23
• InChiKey: WDUQOKAMYKEBRG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  96.5
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• AGENT FOR INDUCING ENDOGENOUS INTERFERON
  申请人：Tets, Viktor Veniaminovich

  公开号：EP2638901A1

  公开（公告）日：2013-09-18

  The invention relates to medicine and can be used for treating a range of diseases in the treatment of which interferon is used. The agent for inducing endogenous interferon is comprised of the compound 6-(3-methoxycarbonyl phenyl) amino-2,4 (1H,3H)-pyrimidinedione C12H11N3O4 of general formula: (I). The preparation exhibits greater activity both when injected and when administered orally.

  本发明涉及医药，可用于治疗一系列使用干扰素的疾病。诱导内源性干扰素的药剂由通式为 6-(3-甲氧羰基苯基)氨基-2,4(1H,3H)-嘧啶二酮 C12H11N3O4 的化合物组成：(I).该制剂在注射和口服时均表现出更强的活性。
• Agent for inducing endogenous interferon
  申请人：Tets Viktor Veniaminovich

  公开号：US10029990B2

  公开（公告）日：2018-07-24

  The invention relates to medicine and can be used for treating a range of diseases in the treatment of which interferon is used. The agent for inducing endogenous interferon is comprised of the compound 6-(3-methoxycarbonyl phenyl) amino-2,4 (1H, 3H)-pyrimidinedione C12H11N3O4 of general formula: (I). The preparation exhibits greater activity both when injected and when administered orally.

  本发明涉及医药，可用于治疗一系列使用干扰素的疾病。诱导内源性干扰素的药剂由通式为 6-(3-甲氧羰基苯基)氨基-2,4(1H,3H)-嘧啶二酮 C12H11N3O4 的化合物组成：(I).该制剂在注射和口服时均表现出更强的活性。