3,6-dimethyltetrahydro-2H-pyran-2-ol | 18397-48-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧烷类
• 英文名称: 3,6-dimethyltetrahydro-2H-pyran-2-ol
• 英文别名: 5-hydroxy-2-methyl-hexanal cyclohemiacetal；3,6-dimethyl-tetrahydro-pyran-2-ol；3,6-Dimethyloxan-2-ol
• CAS: 18397-48-3
• 化学式: C₇H₁₄O₂
• 分子量: 130.187
• InChiKey: NYXLQTGDRPKUNG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  9
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  3,6-dimethyltetrahydro-2H-pyran-2-ol 在 对甲苯磺酸 作用下， 生成 2,5-dimethyl-3,4-dihydro-2H-pyran
  参考文献：
  名称：

  Colonge,J.; Guigues,F., Bulletin de la Societe Chimique de France, 1967, p. 3881 - 3888

  摘要：

  DOI：
• 作为产物：
  描述：

  5-cyano-2-hexanone 在 钾硼氢 作用下， 生成 3,6-dimethyltetrahydro-2H-pyran-2-ol
  参考文献：
  名称：

  Colonge,J.; Guigues,F., Bulletin de la Societe Chimique de France, 1967, p. 3881 - 3888

  摘要：

  DOI：

文献信息

• Remote Control of Regio- and Diastereoselectivity in the Hydroformylation of Bishomoallylic Alcohols with Catalytic Amounts of a Reversibly Bound Directing Group
  作者：Christian U. Grünanger、Bernhard Breit

  DOI：10.1002/anie.200905949

  日期：2010.1.25

  Remote and reversible! Phosphinites serve as reversibly bound directing groups for the remote control of the regio‐ and diastereoselective hydroformylation of bishomoallylic alcohols (see scheme; r.r: regioisomer ratio). The distance between the double bond and the functional hydroxy group to which the directing group is reversibly bound is the longest ever reported.

  远程且可逆！次膦酸酯是可逆结合的导向基团，用于远程控制双烯丙基烯丙醇的区域和非对映选择性加氢甲酰化（请参阅方案； rr：区域异构体比率）。双键与可逆结合的方向性羟基基团之间的距离是有史以来最长的。
• Macrolides and Alcohols as Scent Gland Constituents of the Madagascan Frog <i>Mantidactylus femoralis</i> and Their Intraspecific Diversity
  作者：Dennis Poth、Pardha Saradhi Peram、Miguel Vences、Stefan Schulz

  DOI：10.1021/np400131q

  日期：2013.9.27

  degree, visual signals are the predominant means of signaling in frogs. Nevertheless, certain lineages such as the mantelline frogs from Madagascar use the chemical communication channel as well. Males possess femoral glands on the hind legs, which recently have been shown to contain volatile compounds used in communication as pheromones. Many mantelline species occur in sympatry, and so far species

  青蛙的声音信号的主要手段是声音信号，在较小程度上，视觉信号也是如此。但是，某些血统，例如马达加斯加的曼陀林蛙，也使用化学交流渠道。雄性在后腿上有股腺，最近已显示它们含有挥发性化合物，可作为信息素进行交流。交联剂中存在许多曼陀罗物种，到目前为止，人们认为物种识别主要是通过声信号发生的。通过GC / MS分析股线疣的腺体成分，发现存在挥发性大环内酯类和仲醇类。新的天然产物扁桃体内酯A（4）和B（6）以及几种甲基甲醇被鉴定出来，并通过合成确认了它们的结构。对来自马达加斯加不同地区的个体进行的分析显示，存在着以化合物的特定模式为特征的两组。虽然一组中包含醇和扁桃内酯B，但另一组显示大环内酯类磷脂I（1）和扁桃内酯A（4）的特定存在。某些人的遗传分析显示，遗传相关性与腺体成分之间没有一致性。来自相关物种的其他几个个体具有不同的腺体组成。这表明更广泛的相关物种可能会使用一套基本的生物合成机制。
• DIHYDROPYRAN COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：JNC CORPORATION

  公开号：US20150252264A1

  公开（公告）日：2015-09-10

  To provide a liquid crystal compound satisfying at least one of physical properties such as high stability to ultraviolet light and heat, a high clearing point, low minimum temperature of a liquid crystal phase, small viscosity, suitable optical anisotropy, large dielectric anisotropy and excellent compatibility with other liquid crystal compounds, and a liquid crystal composition containing the compound, and a liquid crystal display device including the composition. The compound includes a compound represented by formula (1): wherein, R a and R b are alkyl or the like; A 1 , A 2 and A 3 are 1,4-cyclohexylene, 1,4-phenylene or the like; G is a divalent group represented by formula (pr-1) or (pr-2); wherein, Z 1 , Z 2 and Z 3 are a single bond, alkylene or the like; and a and b are 0, 1, 2 or 3, and a sum of a and b is 4 or less.

  提供一种液晶化合物，满足至少一种物理性质，如对紫外线和热的高稳定性、高清晰点、液晶相的最低温度低、小粘度、适当的光学各向异性、大介电各向异性以及与其他液晶化合物的良好相容性，并提供一种包含该化合物的液晶组合物和一种包括该组合物的液晶显示装置。该化合物包括式（1）所表示的化合物：其中，Ra和Rb是烷基或类似物；A1、A2和A3是1,4-环己烯基、1,4-苯基或类似物；G是由式（pr-1）或（pr-2）所表示的二价基团；其中，Z1、Z2和Z3是单键、烷基或类似物；a和b分别为0、1、2或3，a和b的总和小于等于4。
• TETRAHYDROPYRAN COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：Masukawa Tokifumi

  公开号：US20120145958A1

  公开（公告）日：2012-06-14

  A compound represented by formula (1-1) or (1-2) is provided. For example, R 1 and R 2 are independently hydrogen, alkyl having 1 to 10 carbons or alkoxy having 1 to 9 carbons; the ring A 1 , the ring A 2 , the ring A 3 , the ring A 4 , the ring A 5 and the ring A 6 are independently 1,4-cyclohexylene or 1,4-phenylene; a, b, c, d, e and f are independently 0 or 1, and the sum of a, b, c, d, e and f is 2; and g, h, i, j, k and l are independently 0 or 1, and the sum of g, h, i, j, k and l is 2.

  提供了由式(1-1)或(1-2)表示的化合物。例如，R1和R2分别独立地表示氢、具有1至10个碳的烷基或具有1至9个碳的烷氧基；环A1、环A2、环A3、环A4、环A5和环A6分别独立地表示1,4-环己基或1,4-苯基；a、b、c、d、e和f分别独立地表示0或1，且a、b、c、d、e和f的和为2；而g、h、i、j、k和l分别独立地表示0或1，且g、h、i、j、k和l的和为2。
• FOUR-RING LIQUID CRYSTAL COMPOUND HAVING TETRAHYDROPYRAN AND 2,2',3,3'-TETRAFLUOROBIPHENYL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：Hirata Kenji

  公开号：US20110297881A1

  公开（公告）日：2011-12-08

  The invention provides a liquid crystal compound that has a large negative dielectric anisotropy (Δ∈) and also has at least one of characteristics such as the stability to heat, light or the like, a high clearing point, a suitable refractive index anisotropy (Δn), a large negative dielectric anisotropy (Δ∈) and an excellent compatibility with other liquid crystal compounds. An excellent effect in which especially the value of the dielectric anisotropy (Δ∈) is increased negatively is achieved by use of the compound having two moieties of 1) a tetrahydropyran ring and and thus the effect is utilized.

  本发明提供了一种液晶化合物，具有较大的负介电各向异性（Δ∈），并且具有至少一种特性，如耐热性、耐光性等稳定性，高清晰点，适当的折射率各向异性（Δn），较大的负介电各向异性（Δ∈）和与其他液晶化合物的良好相容性。通过使用具有1）四氢吡喃环和2）二苯基甲烷基团的化合物，特别是负介电各向异性（Δ∈）值得到提高，从而利用了该效应。