(E)-4-benzylsulfonylbut-2-enenitrile

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (E)-4-benzylsulfonylbut-2-enenitrile
• 化学式: C₁₁H₁₁NO₂S
• 分子量: 221.28
• InChiKey: OWNAZSAHTAXVBZ-SNAWJCMRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  66.3
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• 4-BENZYLSULFONYL-2-BUTENENITRILE
  申请人：Olatec Therapeutics LLC

  公开号：US20160361286A1

  公开（公告）日：2016-12-15

  The present invention is directed to a pharmaceutical composition comprising a pharmaceutically acceptable carrier and 4-benzylsulfonyl-2-butenenitrile, or a pharmaceutically acceptable salt or solvate thereof. The present invention is directed to a method for treating inflammation, inflammatory-related disorders, or pain, by administering 4-benzylsulfonyl-2-butenenitrile, or a pharmaceutically acceptable salt or solvate thereof to a subject in need thereof.

  本发明涉及一种包含药用载体和4-苄基磺酰基-2-丁烯腈或其药用可接受的盐或溶剂的药物组合物。本发明涉及一种治疗炎症、炎症相关疾病或疼痛的方法，通过向需要的受试者施用4-苄基磺酰基-2-丁烯腈或其药用可接受的盐或溶剂。
• US9987246B2
  申请人：——

  公开号：US9987246B2

  公开（公告）日：2018-06-05
• [EN] 4-BENZYLSULFONYL-2-BUTENENITRILE<br/>[FR] 4-BENZYLSULFONYL-2-BUTÈNENITRILE
  申请人：OLATEC IND LLC

  公开号：WO2015130595A1

  公开（公告）日：2015-09-03

  The present invention is directed to a pharmaceutical composition comprising a pharmaceutically acceptable carrier and 4-benzylsulfonyl-2-butenenitrile, or a pharmaceutically acceptable salt or solvate thereof. The present invention is directed to a method for treating inflammation, inflammatory-related disorders, or pain, by administering 4-benzylsulfonyl-2-butenenitrile, or a pharmaceutically acceptable salt or solvate thereof to a subject in need thereof.