N-methylbenzenaminium acetate | 26537-25-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-methylbenzenaminium acetate
• 英文别名: acetic acid;N-methylaniline
• CAS: 26537-25-7
• 化学式: C₂H₄O₂*C₇H₉N
• 分子量: 167.208
• InChiKey: PKQNYEVPNZZQFR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.82
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  49.3
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  溶剂黄146 、 N-甲基苯胺 以99%的产率得到N-methylbenzenaminium acetate
  参考文献：
  名称：

  Efficient, direct α-methylenation of carbonyls mediated by diisopropylammonium trifluoroacetate

  摘要：

  介绍了一种直接将羰基化合物进行α-亚甲基化的非常高效的方法，产率高达99%，该方法利用了多聚甲醛、二异丙基胺三氟乙酸盐以及催化量的酸或碱。

  DOI：

  10.1039/b924577d

文献信息

• CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS
  申请人：Henkel IP & Holding GmbH

  公开号：US20170174630A1

  公开（公告）日：2017-06-22

  Cure accelerators for anaerobic curable compositions, such as adhesives and sealants, are provided, and which are defined with reference to the compounds shown in structure I where A is CH 2 or benzyl, R is C 1-10 alkyl, R′ is H or C 1-10 alkyl, or R and R′ taken together may form a four to seven membered ring fused to the benzene ring, R″ is optional, but when R″ is present, R″ is halogen, alkyl, alkenyl, cycloalkyl, hydroxyalkyl, hydroxyalkenyl, alkoxy, amino, alkylene- or alkenylene-ether, alkylene (meth)acrylate, carbonyl, carboxyl, nitroso, sulfonate, hydroxyl or haloalkyl, and EWG is as shown, an electron withdrawing group, such as nitro, nitrile, carboxylate or trihaloalkyl.

  为氧化还原固化组合物（如胶粘剂和密封剂）提供了用于加速固化的固化催化剂，其定义参考结构I中显示的化合物，其中A为CH2或苄基，R为C1-10烷基，R′为H或C1-10烷基，或者R和R′一起可以形成与苯环融合的四至七元环，R″是可选的，但当R″存在时，R″是卤素、烷基、烯基、环烷基、羟基烷基、羟基烯基、烷氧基、氨基、烷基-或烯基-醚、烷基（甲基）丙烯酸酯、羰基、羧基、亚硝基、磺酸酯、羟基或卤代烷基，以及EWG如所示，是一种电子吸引基团，如硝基、腈基、羧酸盐或三卤代烷基。
• Hair cosmetic, aminocarboxylic acid amide and method for producing the same
  申请人：Kao Corporation

  公开号：US20030035784A1

  公开（公告）日：2003-02-20

  A hair cosmetic which can impart, to hairs, flexibility, smoothness and oily feeling when the hairs are wetted and smoothness, softness and combing easiness after the hairs are dried are provided, the hair cosmetic comprising an amine represented by the formula (I): Formula (I) 1 (wherein R 1 represents a C 8-40 alkyl group or alkenyl group or a group represented by the formula R 5 O—(AO) n —C m H 2m — (R 5 represents a C 8-40 alkyl group or alkenyl group having 8 to 40 carbon atoms, A represents a C 2-3 alkylene group, n denotes a number from 0 to 30 in average and m denotes an integer of 2 or 3), R 2 represents a C 1-5 alkylene group, R 3 represents H, a C 1-24 alkyl group, alkenyl group or hydroxyalkyl group or a C 6-28 aryl group or arylalkyl group, R 4 represents H, a C 1-5 alkyl group, alkylene group or hydroxyalkyl group or a C 6-28 aryl group or arylalkyl group, p denotes an integer from 1 to 3, q and r denote integers from 0 to 2 and p+q+r is equal to 3. Also, the amine (I) can be produced with high selectivity and highly economically by reacting a primary amine with an aminocarboxylic acid to run amidation. An amine represented by the formula (1), its salt or quaternary ammonium salt are also provided: Formula (1) 2

  提供一种头发化妆品，它可以在头发被浸湿时赋予头发柔软、光滑和油腻的感觉，并在头发干燥后提供光滑、柔软和易于梳理的效果。该头发化妆品包括一种由式(I)表示的胺：式(I)1（其中，R1表示C8-40烷基或烯基或由式R5O-（AO）n-CmH2m-表示的基团（其中，R5表示具有8至40个碳原子的C8-40烷基或烯基，A表示C2-3烷基，n表示平均值为0至30的数字，m表示2或3的整数），R2表示C1-5烷基，R3表示H、C1-24烷基、烯基或羟基烷基或C6-28芳基基团或芳基烷基基团，R4表示H、C1-5烷基、烷基或羟基烷基或C6-28芳基基团或芳基烷基基团，p表示1至3的整数，q和r表示0至2的整数，且p+q+r等于3。此外，胺（I）可以通过将一种一级胺与一种氨基羧酸反应以进行酰胺化，从而高选择性、高经济性地生产。还提供一种由式（1）表示的胺、其盐或季铵盐：式（1）2。
• Two part curable composition
  申请人：Henkel IP & Holding GmbH

  公开号：US10689504B2

  公开（公告）日：2020-06-23

  Two part curable compositions are provided, which include a cure accelerator defined with reference to compounds shown in structure I where A is CH2 or benzyl, R is C1-10 alkyl, R′ is H or C1-10 alkyl, or R and R′ taken together may form a four to seven membered ring fused to the benzene ring, R″ is optional, but when R″ is present, R″ is halogen, alkyl, alkenyl, cycloalkyl, hydroxyalkyl, hydroxyalkenyl, alkoxy, amino, alkylene- or alkenylene-ether, alkylene (meth)acrylate, carbonyl, carboxyl, nitroso, sulfonate, hydroxyl or haloalkyl, and EWG is as shown, an electron withdrawing group, such as nitro, nitrile, carboxylate or trihaloalkyl.

  提供了双组分固化组合物，其中包括一种固化促进剂，其定义参考了结构 I 所示的化合物 其中 A 是 CH2 或苄基，R 是 C1-10 烷基，R′ 是 H 或 C1-10 烷基，或 R 和 R′合在一起可形成一个与苯环熔合的四至七个成员的环，R″ 是任选的，但当 R″ 存在时，R″ 是卤素、烷基、烯基、环烷基、羟基烷基、烷氧基、氨基、亚烷基或亚烷基醚、亚烷基（烷基）或亚烷基（烷基）醚、烷氧基、氨基、亚烷基或亚烯基醚、亚烷基（甲基）丙烯酸酯、羰基、羧基、亚硝基、磺酸基、羟基或卤代烷基，而 EWG 如图所示，是一个取电子基团，如硝基、腈基、羧基或三卤代烷基。
• NOVEL PIPERIDINE DERIVATIVES WITH PAF ANTAGONIST ACTIVITY
  申请人：J. URIACH & CIA. S.A.

  公开号：EP0738269A1

  公开（公告）日：1996-10-23
• PIPERIDINE DERIVATIVES WITH PAF ANTAGONIST ACTIVITY
  申请人：J. URIACH & CIA. S.A.

  公开号：EP0738269B1

  公开（公告）日：2000-04-26