2-pyridin-3-yl-N-[(E)-[6-[2-(2-pyridin-3-ylethanethioyl)hydrazinyl]-1,3,5-dioxazin-4-ylidene]amino]ethanethioamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2-pyridin-3-yl-N-[(E)-[6-[2-(2-pyridin-3-ylethanethioyl)hydrazinyl]-1,3,5-dioxazin-4-ylidene]amino]ethanethioamide
• 化学式: C₁₇H₁₇N₇O₂S₂
• 分子量: 415.5
• InChiKey: WULFNUJDEWWKQW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  28
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  169
• 氢给体数：
  3
• 氢受体数：
  7

文献信息

• EP2057118B1
  申请人：——

  公开号：EP2057118B1

  公开（公告）日：2015-03-04
• COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS
  申请人：Koya Keizo

  公开号：US20100093828A1

  公开（公告）日：2010-04-15

  Disclosed are compounds of formula (IA), formula (IV) or formula (V), and pharmaceutical compositions containing them which are useful for treating a subject with a proliferative disorder, such as cancer. The disclosed compounds and pharmaceutical compositions are also useful for treating disorders responsive to Hsp 70 induction and/or natural killer induction.
• Compounds For The Treatment Of Proliferative Disorders
  申请人：Synta Pharmaceuticals Corp.

  公开号：US20150080386A1

  公开（公告）日：2015-03-19

  Disclosed are compounds and pharmaceutical compositions that are useful for treating a subject with a proliferative disorder, such as cancer. The disclosed compounds and pharmaceutical compositions are also useful for treating disorders responsive to Hsp70 induction and/or natural killer induction.
• US8785451B2
  申请人：——

  公开号：US8785451B2

  公开（公告）日：2014-07-22
• US9102601B2
  申请人：——

  公开号：US9102601B2

  公开（公告）日：2015-08-11