5-Methyl-2-(pyridin-2-yldisulfanyl)pyridine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 5-Methyl-2-(pyridin-2-yldisulfanyl)pyridine
• 英文别名: 5-methyl-2-(pyridin-2-yldisulfanyl)pyridine
• 化学式: C₁₁H₁₀N₂S₂
• 分子量: 234.3
• InChiKey: DQTKJFGTEGRXIC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  76.4
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• CROSSLINKED POLYMER NANO-ASSEMBLIES AND USES THEREOF
  申请人：University of Massachusetts

  公开号：US20190083649A1

  公开（公告）日：2019-03-21

  The invention provides powerful methods and compositions for designing, selecting, fine-tuning and optimizing polymer nanogel and other supramolecular assemblies for various properties including, for example, particle size, density and morphology, guest loading capacity and encapsulation stability, and dynamic release control.

  本发明提供了设计、选择、微调和优化聚合物纳米凝胶和其他超分子组装体以获得各种性质的强大方法和组合物，包括但不限于粒径、密度和形态、客体负载能力和封装稳定性以及动态释放控制。
• OLIGONUCLEOTIDE DERIVATIVE OR SALT THEREOF
  申请人：KYOWA KIRIN CO., LTD.

  公开号：US20210108207A1

  公开（公告）日：2021-04-15

  The present invention provides, for example, an oligonucleotide derivative or a salt thereof comprising a circular oligonucleotide and a linear oligonucleotide, wherein the circular oligonucleotide and the linear oligonucleotide have base sequences complementary to each other, and form a complex via a hydrogen bond between the complementary base sequences, and a method for producing the same.
• COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATMENT OF DISEASES INVOLVING ACIDIC OR HYPOXIC DISEASED TISSUES
  申请人：Cybrexa 1, Inc.

  公开号：US20210299137A1

  公开（公告）日：2021-09-30

  Compounds for treatment of diseases having acidic or hypoxic diseased tissues and pharmaceutical compositions comprising the compounds, as well as methods for making and using the compounds and compositions.
• Lipid Nanoparticles for Delivery of Nucleic Acids and Methods of Use Thereof
  申请人：Akagera Medicines, Inc.

  公开号：US20220411394A1

  公开（公告）日：2022-12-29

  The present disclosure provides for improved compositions of ionizable lipid nanoparticles for the delivery of therapeutic nucleic acids to cells. Cationic ionizable lipids are engineered with improved stability to oxidative degradation while in storage, while retaining high transfection activity or potency in cells. These lipids are designed to be biodegradable, thus improving the tolerability of nanoparticles formed with them in vivo. In addition, targeting of these nanoparticles in a highly specific manner to dendritic cells is provided for through inclusion of antibody conjugates directed against cell surface receptors.
• US9795689B2
  申请人：——

  公开号：US9795689B2

  公开（公告）日：2017-10-24