(5-Chloro-2-fluorophenyl)(methyl)sulfane

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: (5-Chloro-2-fluorophenyl)(methyl)sulfane
• 英文别名: 4-chloro-1-fluoro-2-methylsulfanylbenzene
• 化学式: C₇H₆ClFS
• 分子量: 176.64
• InChiKey: PDZVUMODZQWQTH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  25.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] METHODS FOR THE IDENTIFICATION, EVALUATION AND TREATMENT OF PATIENTS HAVING MULTIPLE MYELOMA<br/>[FR] MÉTHODES POUR L'IDENTIFICATION, L'ÉVALUATION ET LE TRAITEMENT DE PATIENTS ATTEINTS D'UN MYÉLOME MULTIPLE
  申请人：MILLENNIUM PHARM INC

  公开号：WO2017079572A1

  公开（公告）日：2017-05-11

  The present disclosure relates to methods for the treatment of multiple myeloma in patients who have one or more cytogenetic alterations. In particular, the disclosure provides methods for treatment of multiple myeloma in patients who have one or more cytogenetic alternations by administering to a patient a treatment regimen comprising a proteasome inhibitor or a pharmaceutically acceptable salt, stereoisomeric or tautomeric form thereof if said patient is identified as a likely responder to the treatment regimen by assessing the presence of said cytogenetic alterations.