3-(4-Hydroxy-3-methylphenyl)-2-methylpropanal

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-(4-Hydroxy-3-methylphenyl)-2-methylpropanal
• 英文别名: 3-(4-hydroxy-3-methylphenyl)-2-methylpropanal
• 化学式: C₁₁H₁₄O₂
• 分子量: 178.23
• InChiKey: WJMZNBYXGTTZEM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Carbidopa and L-Dopa Prodrugs and Methods of Use
  申请人：AbbVie Inc.

  公开号：US20160106765A1

  公开（公告）日：2016-04-21

  The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.

  本公开涉及（a）卡比多巴前药，（b）包括卡比多巴前药和/或L-多巴前药的药物组合和组成物，以及（c）治疗帕金森病和相关疾病的方法，包括向患有帕金森病的受试者施用卡比多巴前药和L-多巴前药。
• Carbidopa And L-Dopa Prodrugs And Methods Of Use
  申请人：AbbVie, Inc.

  公开号：US20160362431A1

  公开（公告）日：2016-12-15

  The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.
• Carbidopa and L-Dopa Prodrugs and Methods of use
  申请人：AbbVie Inc.

  公开号：US20180079762A1

  公开（公告）日：2018-03-22

  The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.
• US9446059B2
  申请人：——

  公开号：US9446059B2

  公开（公告）日：2016-09-20