申请人:SUZUKI Nobuyasu
公开号:US20070105899A1
公开(公告)日:2007-05-10
The present invention provides novel benzene compounds presented by the following formulas, and analogs thereof, that exert an ACC activity-inhibiting effect that is effective in the treatment of obesity, hyperlipemia, fatty liver, hyperglycemia, impaired glucose tolerance, diabetes, diabetic complications (diabetic peripheral neuropathy, diabetic nephropathy, diabetic retinopathy, and diabetic macroangiopathy, hypertension, arteriosclerosis), hypertension, and arteriosclerosis.
本发明提供了以下公式所示的新型苯化合物及其类似物,具有ACC活性抑制作用,对肥胖、高脂血症、脂肪肝、高血糖、糖耐量受损、糖尿病、糖尿病并发症(糖尿病周围神经病变、糖尿病肾病、糖尿病视网膜病变和糖尿病大血管病变、高血压、动脉硬化)以及高血压和动脉硬化的治疗有效。