bis(2-hydroxyethyl) phenylphosphonate | 59259-22-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机膦酸及其衍生物
• 英文名称: bis(2-hydroxyethyl) phenylphosphonate
• 英文别名: di(2-hydroxyethyl)phenylphosphonate；Di-O-β-hydroxyaethyl-phenylphosphonat；Bis(2-hydroxyethyl) phenylphosphonate；2-[2-hydroxyethoxy(phenyl)phosphoryl]oxyethanol
• CAS: 59259-22-2
• 化学式: C₁₀H₁₅O₅P
• 分子量: 246.2
• InChiKey: ZUTCWSCGHFIJPZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  16
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  76
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  bis(2-hydroxyethyl) phenylphosphonate 生成 2-phenyl-[1,3,2]dioxaphospholane-2-oxide
  参考文献：
  名称：

  Costisella,B.; Gross,H., Journal fur praktische Chemie (Leipzig 1954), 1975, vol. 317, p. 798 - 806

  摘要：

  DOI：
• 作为产物：
  描述：

  环氧乙烷 、 苯膦酸 以 苯 为溶剂， 生成 bis(2-hydroxyethyl) phenylphosphonate
  参考文献：
  名称：

  Costisella,B.; Gross,H., Journal fur praktische Chemie (Leipzig 1954), 1975, vol. 317, p. 798 - 806

  摘要：

  DOI：

文献信息

• Method and compositions for identifying anti-HIV therapeutic compounds
  申请人：Arimilli N. Murty

  公开号：US20050239054A1

  公开（公告）日：2005-10-27

  Methods are provided for identifying anti-HIV therapeutic compounds substituted with carboxyl ester or phosphonate ester groups. Libraries of such compounds are screened optionally using the novel enzyme GS-7340 Ester Hydrolase. Compositions and methods relating to GS-7340 Ester Hydrolase also are provided.

  提供了一种识别含有羧酸酯或磷酸酯基团取代的抗HIV治疗化合物的方法。可以选择使用新型酶GS-7340酯水解酶对这类化合物库进行筛选。还提供了与GS-7340酯水解酶相关的组合物和方法。
• Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds
  申请人：Arimilli N. Murty

  公开号：US20050209197A1

  公开（公告）日：2005-09-22

  Phosphonate substituted compounds with HIV protease inhibitory properties having use as therapeutics and for other industrial purposes are disclosed. The compositions inhibit HIV protease activity and/or are useful therapeutically for the treatment of AIDS and other antiviral infections, as well as in assays for the detection of HIV protease.

  本发明揭示了具有抗HIV蛋白酶活性的膦酸酯取代化合物，可用作治疗剂和其他工业用途。该组合物抑制HIV蛋白酶活性和/或在治疗艾滋病和其他抗病毒感染方面有用，以及在检测HIV蛋白酶的测定中有用。
• Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds
  申请人：Arimilli N. Murty

  公开号：US20070010489A1

  公开（公告）日：2007-01-11

  Phosphonate substituted compounds with HIV protease inhibitory properties having use as therapeutics and for other industrial purposes are disclosed. The compositions inhibit 5 HIV protease activity and/or are useful therapeutically for the treatment of AIDS and other antiviral infections, as well as in assays for the detection of HIV protease.

  本发明揭示了具有HIV蛋白酶抑制剂性质的膦酸酯取代化合物，其具有作为治疗剂和其他工业用途的用途。该组合物抑制5型HIV蛋白酶活性和/或在治疗艾滋病和其他抗病毒感染方面具有治疗作用，以及在检测HIV蛋白酶方面的检测中有用。
• ADHESIVE FOR TEETH-STRAIGHTENING MEMBERS
  申请人：Nihon University

  公开号：EP2149360A1

  公开（公告）日：2010-02-03

  The present invention discloses an adhesive for orthodontic attachments, which contains (A) a polymerizable monomer, (B) a polymerization initiator and (C) a fluorescent dye and, when cured, exhibits a fluorescence spectrum having a peak at 400 to 800 nm. As the polymerization initiator (B), there is preferably used a compound which generates a radical through the transfer of hydrogen between two components, or a compound which generates a radical species through intramolecular cleavage. As the fluorescent dye (C), a coumarin type dye is used preferably.

  本发明公开了一种用于正畸附件的粘合剂，它含有 (A) 一种可聚合单体，(B) 一种聚合引发剂和 (C) 一种荧光染料，当固化时，其荧光光谱的峰值在 400 至 800 纳米之间。作为聚合引发剂（B），最好使用通过两个组分之间的氢转移产生自由基的化合物，或通过分子内裂解产生自由基的化合物。作为荧光染料（C），最好使用香豆素类染料。
• POLYESTER FIBER, PROCESS FOR PRODUCING THE POLYESTER FIBER, AND TIRE CODE, TIRE, FIBER MATERIAL FOR REINFORCING BELT AND BELT EACH COMPRISING THE POLYESTER FIBER
  申请人：Teijin Fibers Limited

  公开号：EP2261403A1

  公开（公告）日：2010-12-15

  There is provided a polyester fiber which has few defects such as voids due to catalyst particles, and low variation in physical properties and minimal fluff generation. The polyester fiber of the invention comprises laminar nanoparticles composed of a divalent metal and a phosphorus compound and having side lengths of 5-100 nm and an interlayer spacing of 1-5 nm. There are also provided a tire cord, tire, belt-reinforcing fiber material and belt, comprising the polyester fiber.

  本发明提供了一种聚酯纤维，其缺陷很少，如催化剂颗粒造成的空隙，物理性能变化小，绒毛产生量极少。本发明的聚酯纤维包括由二价金属和磷化合物组成的层状纳米颗粒，其边长为 5-100 纳米，层间间距为 1-5 纳米。此外，还提供了一种由聚酯纤维组成的轮胎帘线、轮胎、带增强纤维材料和带。