[4-[[(2-Ethylphenyl)carbamoyl-(2-methylpropyl)amino]methyl]phenyl] methanesulfonate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [4-[[(2-Ethylphenyl)carbamoyl-(2-methylpropyl)amino]methyl]phenyl] methanesulfonate
• 化学式: C₂₁H₂₈N₂O₄S
• 分子量: 404.5
• InChiKey: PLFSBXLGZFNVGB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  28
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  84.1
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• MODULATION OF DYNEIN IN SKIN
  申请人：Avon Products, Inc.

  公开号：EP2659004B1

  公开（公告）日：2017-08-30
• Cosmetic Use of N-Substituted Sulfonyloxybenzylamines and Related Compounds
  申请人：Ptchelintsev Dmitri S.

  公开号：US20120004302A1

  公开（公告）日：2012-01-05

  Cosmetic compositions comprising N-substituted sulfonyloxybenzylamines and methods of using such compositions to impart anti-aging benefits to the skin are disclosed. The N-substituted sulfonyloxybenzylamines are believed to have modulatory activity against one or more biochemical pathways implicated in skin aging.
• Modulation of Dynein in Skin
  申请人：ZHENG Qian

  公开号：US20120171133A1

  公开（公告）日：2012-07-05

  Methods for preventing, ameliorating, or reducing dermatological signs of aging are provided which employ active agents that modulate dynein expression in the skin. Also provided are methods for screening for substances which modulate dynein expression levels and the methods of using active agents identified by the screening protocol in the treatment of skin.
• US8815265B2
  申请人：——

  公开号：US8815265B2

  公开（公告）日：2014-08-26
• US9409860B2
  申请人：——

  公开号：US9409860B2

  公开（公告）日：2016-08-09