2-(2'-hydroxy[1,1';3',1'']terphenyl-5'-ylmethylidene)indan-1,3-dione

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(2'-hydroxy[1,1';3',1'']terphenyl-5'-ylmethylidene)indan-1,3-dione
• 英文别名: 2-({6-Hydroxy-5-phenyl-[1,1'-biphenyl]-3-YL}methylidene)-2,3-dihydro-1H-indene-1,3-dione；2-[(4-hydroxy-3,5-diphenylphenyl)methylidene]indene-1,3-dione
• 化学式: C₂₈H₁₈O₃
• mdl: MFCD14711155
• 分子量: 402.449
• InChiKey: PSRMTVORJHBXBA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  31
• 可旋转键数：
  3
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  54.4
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  1,3-茚满二酮 、 2'-羟基-1,1':3',1''-三联苯-5'-甲醛 以 正丁醇 为溶剂， 反应 0.5h， 以70%的产率得到2-(2'-hydroxy[1,1';3',1'']terphenyl-5'-ylmethylidene)indan-1,3-dione
  参考文献：
  名称：

  Reaction of 2′-hydroxy[1,1′;3′,1″]terphenyl-5′-carbaldehyde with 2-naphthylamine and 1,3-diketones

  摘要：

  The condensation of 2'-hydroxy[ 1.1';3', 1"]terphenyl-5'-carbaldehyde with 2-naphthylamine and 1.3-cyclohexanedione or dimedone gave 7,8,9,10,11,12-hexahydrobenzo[a]acridin-11-ones, while analogous three-component condensation with 1,3-indandione afforded azaindeno[1,2-b]phenanthren-12-one. In addition, hexahydro-2H-xanthene-1,8-diones and arylmethylenebisdiketones were isolated as by-products.

  DOI：

  10.1134/s1070428006010167

文献信息

• Reaction of 2′-hydroxy-1,1′: 3′,1″-terphenyl-5′-carbaldehyde with naphthalen-1-amine, quinolin-8-amine, and 1,3-diketones
  作者：A. L. Kurlovich、V. A. Tarasevich、N. G. Kozlov

  DOI：10.1134/s1070428009100133

  日期：2009.10

  Condensation of 2'-hydroxy-1,1': 3',1aEuro(3)-terphenyl-5'-carbaldehyde with naphthalen-1-amine and cyclohexane-1,3-dione, methyl 2,2-dimethyl-4,6-dioxocyclohexane-1-carboxylate, or dimedone gave the corresponding 7-(2'-hydroxy-1,1': 3',1aEuro(3)-terphenyl-5'-yl)-7,8,9,10,11,12-hexahydro-12H-benzo[c]acridin-8-ones. The reaction of 2'-hydroxy-1,1': 3',1aEuro(3)-terphenyl-5'-carbaldehyde with naphthalen-1-amine and indan-1,3-dione produced 7-(2'-hydroxy-1,1': 3',1aEuro(3)-terphenyl-5'-yl)-8H-benzo[h]indeno[1,2-b]quinolin-8-one. 7-(2'-Hydroxy-1,1': 3',1aEuro(3)-terphenyl-5'-yl)-7,8,9,10,11,12-hexahydrobenzo[b][1,10]phenanthrolin-8-ones were obtained by three-component condensation of 2'-hydroxy-1,1': 3',1aEuro(3)-terphenyl-5'-carbaldehyde with quinolin-8-amine and cyclohexane-1,3-dione, methyl 2,2-dimethyl-4,6-dioxocyclohexane-1-carboxylate, or dimedone.
• Reaction of 2′-hydroxy[1,1′;3′,1″]terphenyl-5′-carbaldehyde with 2-naphthylamine and 1,3-diketones
  作者：N. G. Kozlov、V. A. Tarasevich、D. A. Vasilevskii、L. I. Basalaeva

  DOI：10.1134/s1070428006010167

  日期：2006.1

  The condensation of 2'-hydroxy[ 1.1';3', 1"]terphenyl-5'-carbaldehyde with 2-naphthylamine and 1.3-cyclohexanedione or dimedone gave 7,8,9,10,11,12-hexahydrobenzo[a]acridin-11-ones, while analogous three-component condensation with 1,3-indandione afforded azaindeno[1,2-b]phenanthren-12-one. In addition, hexahydro-2H-xanthene-1,8-diones and arylmethylenebisdiketones were isolated as by-products.