(12E)-1,17-dihydroxy-10,11-dimethoxy-14,16-dimethyl-5-phenyl-4,19-dioxabicyclo[13.3.1]nonadec-12-en-3-one

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 大环内酯类和类似物
• 英文名称: (12E)-1,17-dihydroxy-10,11-dimethoxy-14,16-dimethyl-5-phenyl-4,19-dioxabicyclo[13.3.1]nonadec-12-en-3-one
• 化学式: C₂₇H₄₀O₇
• 分子量: 476.6
• InChiKey: OXVNCMXNUOQTIY-CCEZHUSRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  34
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  94.4
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• NEOSORAPHENS AND THEIR USE IN THE TREATMENT OR PREVENTION OF A VIRAL INFECTION OR OF A TH17-ASSOCIATED INFLAMMATORY AND/OR AUTOIMMUNE DISEASE
  申请人：Helmholtz-Zentrum für Infektionsforschung GmbH

  公开号：EP3129385B1

  公开（公告）日：2018-06-06
• NEOSORAPHENS
  申请人：Helmoltz-Zentrum für Infektionsforschung GmbH

  公开号：US20170029436A1

  公开（公告）日：2017-02-02

  The present invention relates to compounds according to general formula (I); to compositions, including a pharmaceutical formulation and a combination preparation comprising one or more of the compound (s); to a process for their preparation; to uses thereof, including the use in the treatment or prevention of a viral infection or a Th17-associated inflammatory and/or autoimmune disease.
• [EN] NEOSORAPHENS<br/>[FR] NÉOSORAPHÈNES
  申请人：HELMHOLTZ ZENTRUM FÜR INFEKTIONSFORSCHUNG GMBH

  公开号：WO2015154883A1

  公开（公告）日：2015-10-15

  The present invention relates to compounds according to general formula (I); to compositions, including a pharmaceutical formulation and a combination preparation comprising one or more of the compound (s); to a process for their preparation; to uses thereof, including the use in the treatment or prevention of a viral infection or a Thl7-associated inflammatory and/or autoimmune disease.