N-[3-(azepane-1-sulfonyl)phenyl]furan-2-carboxamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-[3-(azepane-1-sulfonyl)phenyl]furan-2-carboxamide
• 英文别名: N-[3-(azepan-1-ylsulfonyl)phenyl]furan-2-carboxamide
• 化学式: C₁₇H₂₀N₂O₄S
• mdl: MFCD04681611
• 分子量: 348.4
• InChiKey: UZYCKBHZMVLSRJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.352
• 拓扑面积：
  88
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Blockers of the growth hormone receptor in disease prevention and treatment
  申请人：UNIVERSITY OF SOUTHERN CALIFORNIA

  公开号：US10246446B2

  公开（公告）日：2019-04-02

  Compounds and methods for treating diseases or conditions affected by the activity or expression of genes/proteins related to human GH, GHR, STAT5, SOCS, IGF-1, insulin are provided. Monoclonal antibodies for treating diseases or conditions related to growth hormone and growth hormone receptor activity are also provided.

  提供了用于治疗受人类 GH、GHR、STAT5、SOCS、IGF-1、胰岛素相关基因/蛋白活性或表达影响的疾病或病症的化合物和方法。还提供了用于治疗与生长激素和生长激素受体活性有关的疾病或病症的单克隆抗体。
• BLOCKERS OF THE GROWTH HORMONE RECEPTOR IN DISEASE PREVENTION AND TREATMENT
  申请人：University of Southern California

  公开号：EP3256465B1

  公开（公告）日：2021-04-07
• [EN] BLOCKERS OF THE GROWTH HORMONE RECEPTOR IN DISEASE PREVENTION AND TREATMENT<br/>[FR] BLOQUEURS DU RÉCEPTEUR DE L'HORMONE DE CROISSANCE UTILISÉS DANS LA PRÉVENTION ET LE TRAITEMENT DE MALADIES
  申请人：UNIV SOUTHERN CALIFORNIA

  公开号：WO2016130901A2

  公开（公告）日：2016-08-18

  Compounds and methods for treating diseases or conditions affected by the activity or expression of genes/proteins related to human GH, GHR, STAT5, SOCS, IGF-1, insulin are provided. Monoclonal antibodies for treating diseases or conditions related to growth hormone and growth hormone receptor activity are also provided.