Dioxidonitrogen(1+)

• 分子结构分类: 无机化合物 - 均质非金属化合物 - 其他非金属有机物
• 英文名称: Dioxidonitrogen(1+)
• 英文别名: nitronium
• 化学式: NO2+
• 分子量: 46.006
• InChiKey: OMBRFUXPXNIUCZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.41
• 重原子数：
  3
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  35.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  5-叔丁基-2-羟基苯甲醛 、 Dioxidonitrogen(1+) 在 碳酸氢钠 、 乙酸乙酯 、 水 、 Brine 、 magnesium sulfate 作用下， 以 乙腈 为溶剂， 反应 1.0h， 以5-tert-butyl-2-hydroxy-3-nitro-benzaldehyde was obtained as yellow solid的产率得到3-nitro-5-tert-butyl-2-hydroxybenzaldehyde
  参考文献：
  名称：

  Triazole compounds

  摘要：

  本发明揭示了如下式(I)的化合物：其中Ar1，X，R3，R4，R5和R6的定义如本文所述。该发明的化合物抑制细胞因子的产生，因此可用于治疗细胞因子介导的疾病。本发明还揭示了制备这些化合物的过程以及包含这些化合物的药物组成物。

  公开号：

  US20050153972A1

文献信息

• Perfluoroalkyl-containing compound
  申请人：Sagami Chemical Research Center

  公开号：US05066795A1

  公开（公告）日：1991-11-19

  A (perfluoroalkyl)dibenzonium salt represented by the following general formula ##STR1## wherein R.sub.f represents a perfluoroalkyl group having 1 to 10 carbon atoms, A represents a sulfur of selenium atom, R.sup.1 and R.sup.2, independently from each other, represent a hydrogen atom or a nitro group, X.sup..crclbar. represents a conjugated base of Bronsted acid, and n is 0 or 1. The said compound is useful as a reagent for introducing a perfluoroalkyl group.

  以下是翻译结果： 一种由下列一般式表示的(perfluoroalkyl)dibenzonium盐：##STR1## 其中R.sub.f表示具有1至10个碳原子的全氟烷基，A表示硫或硒原子，R.sup.1和R.sup.2独立地表示氢原子或硝基，X.sup..crclbar.表示BronSTed酸的共轭碱，n为0或1。该化合物可用作引入全氟烷基的试剂。
• SYSTEM AND PROCESS FOR PRODUCTION OF NITROBENZENE
  申请人：Hassan Abbas

  公开号：US20090005615A1

  公开（公告）日：2009-01-01

  A method for producing nitrobenzene is disclosed which comprises forming a dispersion comprising benzene-containing droplets or particles dispersed in a mixture of concentrated nitric acid and concentrated sulfuric acid, wherein said particles have a mean diameter less than one micron, and subjecting the dispersion to reaction conditions comprising a pressure in the range of about 203 kPa (2 atm) to about 6080 kPa (60 atm) and a temperature in the range of about 20° C. to about 230° C., whereby at least a portion of said benzene is nitrated to form nitrobenzene. A system for carrying out the method is also disclosed.

  本发明公开了一种生产硝基苯的方法，其中包括形成一种分散体，该分散体包括分散在浓硝酸和浓硫酸混合物中的苯含量的液滴或颗粒，其中所述颗粒的平均直径小于1微米，并将该分散体置于反应条件下，所述反应条件包括压力在约203千帕（2大气压）至约6080千帕（60大气压）之间，温度在约20℃至约230℃之间，从而至少部分所述苯被硝化成硝基苯。还公开了一种用于执行该方法的系统。
• BICYCLIC COMPOUNDS AND USE AS ANTIDIABETICS
  申请人：Fang Jing

  公开号：US20100029650A1

  公开（公告）日：2010-02-04

  The present invention relates to novel compounds that are useful in the treatment of metabolic disorders, particularly type II diabetes mellitus and related disorders, and also to the methods for the making and use of such compounds.

  本发明涉及一种新型化合物，其在代谢性疾病的治疗中具有用途，特别是在II型糖尿病及相关疾病的治疗中，并且还涉及制备和使用这种化合物的方法。
• Bicyclic compounds and use as antidiabetics
  申请人：GlaxoSmithKline LLC

  公开号：US08101634B2

  公开（公告）日：2012-01-24

  The present invention relates to novel compounds that are useful in the treatment of metabolic disorders, particularly type II diabetes mellitus and related disorders, and also to the methods for the making and use of such compounds.

  本发明涉及一种新型化合物，可用于治疗代谢性疾病，特别是II型糖尿病及相关疾病，并且还涉及制备和使用这种化合物的方法。
• System and process for production of nitrobenzene
  申请人：H R D Corporation

  公开号：US08153077B2

  公开（公告）日：2012-04-10

  A method for producing nitrobenzene is disclosed which comprises forming a dispersion comprising benzene-containing droplets or particles dispersed in a mixture of concentrated nitric acid and concentrated sulfuric acid, wherein said particles have a mean diameter less than one micron, and subjecting the dispersion to reaction conditions comprising a pressure in the range of about 203 kPa (2 atm) to about 6080 kPa (60 atm) and a temperature in the range of about 20° C. to about 230° C., whereby at least a portion of said benzene is nitrated to form nitrobenzene. A system for carrying out the method is also disclosed.

  本发明公开了一种生产硝基苯的方法，其中包括形成一种分散体，该分散体包含分散在浓硝酸和浓硫酸混合物中的苯含量的液滴或颗粒，其中所述颗粒的平均直径小于一微米，并将所述分散体置于反应条件下，包括压力在约203千帕（2大气压）至约6080千帕（60大气压）的范围内和温度在约20℃至约230℃的范围内，从而使得至少一部分所述苯被硝化以形成硝基苯。本发明还公开了一种用于实施该方法的系统。