(4S)-4-(ethylamino)-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: (4S)-4-(ethylamino)-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide
• 化学式: C₉H₁₄N₂O₂S₃
• 分子量: 278.4
• InChiKey: ZEBVHVKGVPQRGW-ZETCQYMHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  134
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION OF KETONE AND AMINE COMPOUNDS
  申请人：CODEXIS, INC.

  公开号：US20220315961A1

  公开（公告）日：2022-10-06

  The present disclosure provides engineered polypeptides having imine reductase activity, polynucleotides encoding the engineered imine reductases, host cells capable of expressing the engineered imine reductases, and methods of using these engineered polypeptides with a range of ketone and amine substrate compounds to prepare secondary and tertiary amine product compounds.