1-(3,4-Dichlorophenyl)-3-[2-(diethylsulfamoyl)-4-nitroanilino]urea

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(3,4-Dichlorophenyl)-3-[2-(diethylsulfamoyl)-4-nitroanilino]urea
• 化学式: C17H19Cl2N5O5S
• 分子量: 476.3
• InChiKey: DRWYFPNVEZDDOR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  30
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  145
• 氢给体数：
  3
• 氢受体数：
  7

文献信息

• Method for Suppressing Freezing Damage and Composition for Preventing Freezing Damage
  申请人：Kyoto University

  公开号：US20210204539A1

  公开（公告）日：2021-07-08

  Provided is a method capable of suppressing cold damage to a biological material such as an organ even if the biological material is preserved at low temperature for a long time, or a composition for preventing cold damage to a biological material. Provided also is a method for suppressing cold damage to a biological material, including inhibiting a sphingosine-1-phosphoric acid (S1P)-mediated signal transduction pathway in the biological material; and a cold damage prevention composition containing, as an active ingredient, a substance that inhibits S1P-mediated signal transduction pathway.