2-(4-((2',6-dimethylbiphenyl-3-yl)methylamino)phenylsulfonyl)acetic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(4-((2',6-dimethylbiphenyl-3-yl)methylamino)phenylsulfonyl)acetic acid
• 英文别名: 2-[4-[[4-Methyl-3-(2-methylphenyl)phenyl]methylamino]phenyl]sulfonylacetic acid；2-[4-[[4-methyl-3-(2-methylphenyl)phenyl]methylamino]phenyl]sulfonylacetic acid
• 化学式: C₂₃H₂₃NO₄S
• 分子量: 409.506
• InChiKey: PNVPMNBYXKFYDY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  29
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  91.8
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• NOVEL AMINO-PHENYL-SULFONYL-ACETATE DERIVATIVES AND USE THEREOF
  申请人：CJ Healthcare Corporation

  公开号：US20170247320A1

  公开（公告）日：2017-08-31

  The present invention relates to a novel amino-phenyl-sulfonyl-acetate derivative or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating diabetes comprising the same as an active ingredient.

  本发明涉及一种新的氨基苯磺酰乙酸盐或其药用可接受盐；以及一种包含其作为活性成分的用于预防或治疗糖尿病的药物组合物。
• NOVEL AMINO-PHENYL-SULFONYL-ACETATE DERIVATIVE AND USE THEREOF
  申请人：CJ Healthcare Corporation

  公开号：EP3187488A1

  公开（公告）日：2017-07-05

  The present invention relates to a novel amino-phenyl-sulfonyl-acetate derivative or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating diabetes comprising the same as an active ingredient.

  本发明涉及一种新型氨基苯磺酰基乙酸酯衍生物或其药学上可接受的盐；以及一种用于预防或治疗糖尿病的药物组合物，其有效成分包括氨基苯磺酰基乙酸酯衍生物或其药学上可接受的盐；以及一种用于预防或治疗糖尿病的药物组合物。
• [EN] NOVEL AMINO-PHENYL-SULFONYL-ACETATE DERIVATIVE AND USE THEREOF<br/>[FR] NOUVEAU DÉRIVÉ D'AMINO-PHÉNYL-SULFONYL-ACÉTATE ET SON UTILISATION<br/>[KO] 신규한 아미노-페닐-설포닐-아세테이트 유도체 및 이의 용도
  申请人：CJ HEALTHCARE CORP

  公开号：WO2016032120A1

  公开（公告）日：2016-03-03

  본 발명은 신규한 아미노-페닐-설포닐-아세테이트 유도체, 또는 이의 약학적으로 허용가능한 염; 및 이를 유효성분으로 포함하는 당뇨병의 예방 또는 치료용 약학적 조성물에 관한 것이다.