E-2-(benzenesulfonylmethylidene)tetrahydrofuran | 74480-93-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: E-2-(benzenesulfonylmethylidene)tetrahydrofuran
• 英文别名: (tetrahydro-2-furylidene)methyl phenyl sulphone；2-[(E)-(phenylsulfonyl)methylidene]tetrahydrofuran；e-2-(Benzenesulfonylmethylidene)-tetrahydrofuran；(2E)-2-(benzenesulfonylmethylidene)oxolane
• CAS: 74480-93-6
• 化学式: C₁₁H₁₂O₃S
• 分子量: 224.28
• InChiKey: QLGNDBHRYNQDLL-MDZDMXLPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  51.8
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  (Z)-5-(benzenesulfonyl)-4-iodopent-4-en-1-ol 以43%的产率得到
  参考文献：
  名称：

  Short Kevin M., Ziegler Carl B., Jr., Tetrahedron Lett., 36 (1995) N 3, S 355-356

  摘要：

  DOI：

文献信息

• Regioselective synthesis of ω-bromo-3-ketosulfones, ω-bromo-3-ketonitriles and 2-(ω-bromoalkyl)benzofurans based on a ‘ring-closing/ring-opening’ strategy
  作者：Nasir Rasool、Muhammad A. Rashid、Helmut Reinke、Christine Fischer、Peter Langer

  DOI：10.1016/j.tet.2007.08.112

  日期：2007.11

  omega-Bromo-3-ketosulfones, omega-bromo-3-ketonitriles and various functionalized 2-(omega-bromoalkyl) benzofurans were chemo-and regioselectively prepared by application of a 'ring-closing/ring-opening' strategy. The cyclization of 3-ketosulfone and 3-ketonitrile dianions with 1-bromo-2-chloroethane or 1,4-dibromobut-2-ene afforded functionalized 2-alkylidenetetrahydrofurans which were subsequently cleaved by reaction with boron tribromide or boron trichloride to give the final products. (c) 2007 Elsevier Ltd. All rights reserved.
• Mussatto, Maria Cristina; Savoia, Diego; Trombini, Claudio, Journal of the Chemical Society. Perkin transactions I, 1980, p. 260 - 263
  作者：Mussatto, Maria Cristina、Savoia, Diego、Trombini, Claudio、Umani-Ronchi, Achille

  DOI：——

  日期：——
• Alzerreca, Arnaldo; Martinez, Judith; Velazquez, Loyda, Journal of Heterocyclic Chemistry, 1994, vol. 31, # 1, p. 45 - 48
  作者：Alzerreca, Arnaldo、Martinez, Judith、Velazquez, Loyda、Prieto, Jose A.、Arias, Luis

  DOI：——

  日期：——
• 5 - and 6 - Membered ring compounds from (E)-β-iodo(vinyl)sulfones
  作者：Kevin M. Short、Carl B. Ziegler

  DOI：10.1016/0040-4039(94)02268-g

  日期：1995.1

  Appropriately functionalized alkynes are converted to (E)-beta-iodo(vinyl)sulfones which, in turn, furnish cyclic products on treatment with base.
• MUSSATO M. C.; SAVOIA D.; TROMBINI C.; UMANI-RONCHI A., J. CHEM. SOC. PERKIN TRANS., 1980, PART 1, NO 1, 260-263,
  作者：MUSSATO M. C.、 SAVOIA D.、 TROMBINI C.、 UMANI-RONCHI A.

  DOI：——

  日期：——