N-[(1S,2R)-2-[diphenyl(phenylimino)-lambda5-phosphanyl]-1-(4-methylphenyl)propyl]aniline | 125295-01-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-[(1S,2R)-2-[diphenyl(phenylimino)-lambda5-phosphanyl]-1-(4-methylphenyl)propyl]aniline
• 英文别名: N-[(1S,2R)-2-[diphenyl(phenylimino)-λ5-phosphanyl]-1-(4-methylphenyl)propyl]aniline
• CAS: 125295-01-4
• 化学式: C₃₄H₃₃N₂P
• 分子量: 500.623
• InChiKey: KTZOWKFOXHZHMA-XQJOSWFISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.9
• 重原子数：
  37
• 可旋转键数：
  8
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  24.4
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  N-(P-甲基苯亚甲基)苯胺 、 ethyldiphenylphosphine N-phenylimide 在 lithium diisopropyl amide 作用下， 生成 N-[(1S,2R)-2-[diphenyl(phenylimino)-lambda5-phosphanyl]-1-(4-methylphenyl)propyl]aniline
  参考文献：
  名称：

  Diastereofacial Selectivity in the Reaction of (C-1)-Metalated Alkyldiphenylphosphine Imides with Schiff Bases

  摘要：

  erythro-2-Anilinoalkyldiphenyphosphine phenylimides are obtained by reaction of (C-1)-metalated alkyldiphenylphosphine imides with aldimines in a diastereoselective fashion. Reaction of the products with carbon dioxide or with lithium aluminum hydride leads to 2-anilinoalkyldiphenylphosphine oxides or 2-anilinoalkyldiphenylphosphines, respectively.

  DOI：

  10.1055/s-1989-27230

文献信息

• Diastereofacial Selectivity in the Reaction of (<i>C</i>-1)-Metalated Alkyldiphenylphosphine Imides with Schiff Bases
  作者：José Barluenga、Fernando López、Francisco Palacios

  DOI：10.1055/s-1989-27230

  日期：——

  erythro-2-Anilinoalkyldiphenyphosphine phenylimides are obtained by reaction of (C-1)-metalated alkyldiphenylphosphine imides with aldimines in a diastereoselective fashion. Reaction of the products with carbon dioxide or with lithium aluminum hydride leads to 2-anilinoalkyldiphenylphosphine oxides or 2-anilinoalkyldiphenylphosphines, respectively.

  erythro-2-Anilinoalkyldiphenyphosphine phenylimides are obtained by reaction of (C-1)-metalated alkyldiphenylphosphine imides with aldimines in a diastereoselective fashion. Reaction of the products with carbon dioxide or with lithium aluminum hydride leads to 2-anilinoalkyldiphenylphosphine oxides or 2-anilinoalkyldiphenylphosphines, respectively.