2-{1-Phenyl-3-[(1-phenylethyl)amino]propyl}phenol

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-{1-Phenyl-3-[(1-phenylethyl)amino]propyl}phenol
• 英文别名: 2-[1-phenyl-3-(1-phenylethylamino)propyl]phenol
• 化学式: C₂₃H₂₅NO
• 分子量: 331.4
• InChiKey: PBCGLNLOJZZAQT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  25
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  32.3
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• SENSE-33 COMPOSITIONS AND METHODS THEREOF FOR ENHANCING THE EXPRESSION AND/OR ACTIVITY OF NICOTINIC ACETYLCHOLINE RECEPTORS
  申请人：Psychis Phaethon

  公开号：US20190083422A1

  公开（公告）日：2019-03-21

  The present disclosure relates to compositions and methods thereof for enhancing the expression and/or function of Nicotinic Acetylcholine Receptors. Specifically, the compositions and methods of the present disclosure employ a family of structurally distinct Phenylalkylamine and diphenylalkylamine derivatives which are selective enhancers of the expression of nicotinic acetylcholine receptors, and/or specific nicotinic acetylcholine receptors subunits.