1-(Pyridin-1-ium-1-yldisulfanyl)pyridin-1-ium

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 1-(Pyridin-1-ium-1-yldisulfanyl)pyridin-1-ium
• 化学式: C10H10N2S2+2
• 分子量: 222.3
• InChiKey: PPOCEYUQYJGGJK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  58.4
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION<br/>[FR] COMPOSITION COLORANTE COMPRENANT AU MOINS UN PRÉCURSEUR DE DISULFURE/THIOL INCOLORE ET PROCÉDÉ DE TEINTURE UTILISANT LA COMPOSITION
  申请人：OREAL

  公开号：WO2009040354A1

  公开（公告）日：2009-04-02

  The present invention relates to the dyeing of keratin materials using two colorless dye precursors, at least one of which contains a disulfide/thiol unit, said precursors reacting together chemically to form the color in situ. The process according to the invention makes it possible in the context of certain variants to solve the problems caused by the color generated during the process, while at the same time not degrading the efficacy of the coloration, and especially of the lightening effect. The colorations obtained are moreover powerful, chromatic, sparingly selective, and fast with respect to external agents such as sunlight, perspiration and especially shampoo.

  本发明涉及使用两种无色染料前体对角蛋白材料进行染色，其中至少一种含有二硫化物/巯基单元，这些前体在化学上相互反应以在原位形成颜色。根据本发明的方法使得在某些变体情况下能够解决染色过程中产生的问题，同时不降低染色的功效，特别是减淡效果。所获得的染色品不仅强大、色彩鲜艳、选择性较少，而且对于阳光、汗水和尤其是洗发水等外部因素具有快速的耐久性。
• Dendrimers as molecular translocators
  申请人：Goodman Murray

  公开号：US20060216265A1

  公开（公告）日：2006-09-28

  Transport molecules include a dendrimer and a biologically active molecule. The dendrimer of such transport molecules includes at least one guanidine group, at least one protonated guanidine group, at least one protected guanidine group, at least one amidine group, at least one protonated amidine group, at least one protected amidine group, at least one ureido group, at least one protonated ureido group, at least one protected ureido group, at least one thioureido group, at least one protonated thioureido group, or at least one protected thioureido group. The biologically active molecule is bonded to the dendrimer. A method of increasing the bioavailability of a drug includes bonding the drug to a dendrimer of the invention.

  转运分子包括一种树枝状聚合物和一种生物活性分子。这些转运分子的树枝状聚合物包括至少一个胍基团、至少一个质子化的胍基团、至少一个保护的胍基团、至少一个酰胺基团、至少一个质子化的酰胺基团、至少一个保护的酰胺基团、至少一个脲基团、至少一个质子化的脲基团、至少一个保护的脲基团、至少一个硫脲基团、至少一个质子化的硫脲基团，或至少一个保护的硫脲基团。生物活性分子与树枝状聚合物结合。一种增加药物生物利用度的方法包括将药物与本发明的树枝状聚合物结合。
• SOLUBLE COMBINATORIAL LIBRARIES
  申请人：——

  公开号：US20030059826A1

  公开（公告）日：2003-03-27

  The present invention relates to novel soluble combinatorial libraries, comprising a soluble phase in solution attached to a core molecule, and allowing the improved high-yield and efficient production of soluble combinatorial libraries. Some specific examples of the soluble combinatorial libraries claimed herein comprise one or more of the following: amino acids, &agr;-azetide amino acids, triazine dione molecules, &ggr;-lactamtide molecules, &dgr;-lactamthiotide molecules, &bgr;-lactam nucleus containing molecules, lycoramine alkaloid nucleus containing molecules, and &bgr;-blocker nucleus molecules. Further, a split synthesis technique for generating libraries of combinatorial molecules employs a biphasic macromolecular support which is soluble during the pooling, splitting, and coupling steps but which is insoluble during the washing step. The use of a biphasic macromolecular support in its soluble phase significantly enhances the efficiency and performance of the pooling, splitting, and coupling steps. The use of a biphasic macromolecular support in its insoluble phase significantly enhances the efficiency and performance of the washing step.

  本发明涉及新型可溶性组合物库，包括溶解相附着在溶液中的核心分子上，并允许改进的高产率和高效的可溶性组合物库的生产。本文所述的可溶性组合物库的一些具体示例包括以下一种或多种：氨基酸，α-氮杂氨基酸，三嗪二酮分子，γ-内酰胺氨基酸，δ-内酰胺硫氨基酸，含有β-内酰胺核的分子，莱科拉明生物碱核含有分子，以及β-阻滞剂核分子。此外，用于生成组合物库的分裂合成技术采用在混合、分裂和偶联步骤期间可溶解但在洗涤步骤期间不溶解的两相高分子支持。在其可溶相中使用两相高分子支持显着增强了混合、分裂和偶联步骤的效率和性能。在其不溶相中使用两相高分子支持显着增强了洗涤步骤的效率和性能。
• [EN] GUANINE ANALOGS AS TELOMERASE SUBSTRATES AND TELOMERE LENGTH AFFECTORS<br/>[FR] ANALOGUES DE GUANINE EN TANT QUE SUBSTRATS DE TÉLOMÉRASE ET AFFECTEURS DE LA LONGUEUR DE TÉLOMÈRES
  申请人：GERON CORP

  公开号：WO2013095684A1

  公开（公告）日：2013-06-27

  This invention relates to compounds useful for inhibiting telomere elongation. More specifically, the invention provides nucleotide analogs that are incorporated into telomeres by telomerase thereby inhibiting elongation of telomeres. The compounds are useful in treating cancer and other cell proliferative diseases.

  这项发明涉及用于抑制端粒延伸的化合物。更具体地说，该发明提供了一种通过端粒酶将核苷酸类似物嵌入端粒中，从而抑制端粒延伸的方法。这些化合物在治疗癌症和其他细胞增殖性疾病方面具有用途。
• STYRYL TETRAHYDROQUINOLINIUM THIOL/DISULFIDE DYE COMPOUND AND METHOD FOR LIGHTENING KERATIN MATERIALS USING THE SAME
  申请人：GREAVES Andrew

  公开号：US20090126125A1

  公开（公告）日：2009-05-21

  The present disclosure relates to the dyeing of keratin materials using thiol/disulfide styryl tetrahydroquinolinium fluorescent dyes. Disclosed herein is a dye composition comprising a thiol/disulfide styryl tetrahydroquinolinium fluorescent dye and a dyeing process with, for instance, a lightening effect on keratin materials such as hair, using said composition. Disclosed herein are thiol fluorescent dyes and the uses thereof in lightening keratin materials. This composition can be used to obtain a lightening effect which can be resistant and visible on dark keratin fibers.

  本公开涉及使用巯基/二硫化物斯亚基四氢喹啉荧光染料对角蛋白材料进行染色。本文公开了一种染料组合物，包括一种巯基/二硫化物斯亚基四氢喹啉荧光染料，以及使用该组合物对角蛋白材料（如头发）进行漂白效果的染色过程。本文还公开了巯基荧光染料及其在漂白角蛋白材料中的用途。该组合物可用于获得对深色角蛋白纤维具有耐久和可见的漂白效果。