Tetrabenzo[b,f,j,n][1,5,9,13]tetraazacyclohexadecine | 450-32-8

• 分子结构分类: 有机化合物 - 苯类化合物
• 英文名称: Tetrabenzo[b,f,j,n][1,5,9,13]tetraazacyclohexadecine
• 英文别名: 2,10,18,26-tetrazapentacyclo[26.4.0.04,9.012,17.020,25]dotriaconta-1,3,5,7,9,11,13,15,17,19,21,23,25,27,29,31-hexadecaene
• CAS: 450-32-8
• 化学式: C₂₈H₂₀N₄
• 分子量: 412.5
• InChiKey: HMQFFFNXKFAEOG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  32
• 可旋转键数：
  0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  49.4
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Sensor for monitoring an analyte
  申请人：——

  公开号：US20040072359A1

  公开（公告）日：2004-04-15

  A food spoilage sensor comprising a macrocyclic transition metal complex of the general formula 1 wherein M is a transition metal ion; D 1 , D 2 , D 3 and D 4 can be the same or different and can be N or P; R 1 and R 2 , R 3 and R 4 , R 5 and R 6 , and R 7 and R 8 can be the same or different and form, taken together with the adjacent carbon atoms to which they are bonded and joined together, an aromatic or a cyclic group with at least one of the aromatic or cyclic groups possessing one or more polymerizable moieties is provided. The complex selectively binds biogenic amines, such as cadaverine, putrescine and histamine, which are released by food spoilage microorganisms. The sensor undergoes a detectable color change upon exposure to biogenic amine, thus indicating that food spoilage has probably occurred. In one embodiment, a polymer containing the macrocyclic transition metal complex is molecularly imprinted with the biogenic amine to impart selective binding affinity such that upon exposure to biogenic amine, a color change is detected.

  一种食品变质传感器，包括一个宏环过渡金属配合物，其一般式为1，其中M是过渡金属离子；D1、D2、D3和D4可以相同或不同，可以是N或P；R1和R2、R3和R4、R5和R6以及R7和R8可以相同或不同，并与它们所连接的相邻碳原子一起形成一个芳香或环状基团，其中至少一个芳香或环状基团具有一个或多个可聚合的基团。该配合物可以选择性地结合生物胺，例如腐败微生物释放的腐胺、亚硝酸盐和组胺。当暴露于生物胺时，传感器会发生可检测的颜色变化，从而表明食品可能已经变质。在一种实施方式中，含有宏环过渡金属配合物的聚合物被分子印迹与生物胺结合，使其具有选择性结合亲和力，当暴露于生物胺时，可以检测到颜色变化。
• US7319038B2
  申请人：——

  公开号：US7319038B2

  公开（公告）日：2008-01-15