Imino-bis(2-nitrophenyl)-$l^{4}-sulfane

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Imino-bis(2-nitrophenyl)-$l^{4}-sulfane
• 英文别名: imino-bis(2-nitrophenyl)-λ4-sulfane
• 化学式: C12H9N3O4S
• 分子量: 291.28
• InChiKey: TZLICMVQPAOMDK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  135
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• Potentiation of cancer therapies by ZNF217 inhibition
  申请人：REGENTS OF THE UNIVERSITY OF CALIFORNIA

  公开号：US20040038322A1

  公开（公告）日：2004-02-26

  This invention provides methods, reagents and kits for treating cancer in a patient or subject, e.g., a human. Accordingly, the present methods can be used to monitor the efficacy of a cancer treatment and to treat cancer, e.g., by inhibiting the expression and/or activity of ZNF217 in a neoplastic cell.

  本发明提供了治疗患者或受试者（例如人类）癌症的方法、试剂和试剂盒。因此，本方法可用于监测癌症治疗的疗效和治疗癌症，例如通过抑制 ZNF217 在肿瘤细胞中的表达和/或活性。
• [EN] POTENTIATION OF CANCER THERAPIES BY ZNF217 INHIBITION<br/>[FR] RENFORCEMENT DE THERAPIES CANCEREUSES PAR INHIBITION DE ZNF217
  申请人：UNIV CALIFORNIA

  公开号：WO2003079748A2

  公开（公告）日：2003-10-02

  This invention provides methods, reagents and kits for treating cancer in a patient or subject, e.g., a human. Accordingly, the present methods can be used to monitor the efficacy of a cancer treatment and to treat cancer, e.g., by inhibiting the expression and/or activity of ZNF217 in a neoplastic cell.