3-Phenyl-propionic acid 2,4,6-trinitro-phenyl ester | 40123-59-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚酯
• 英文名称: 3-Phenyl-propionic acid 2,4,6-trinitro-phenyl ester
• 英文别名: 2,4,6-Trinitrophenyl 3-phenylpropanoate；(2,4,6-trinitrophenyl) 3-phenylpropanoate
• CAS: 40123-59-9
• 化学式: C₁₅H₁₁N₃O₈
• 分子量: 361.268
• InChiKey: WEDKQIHKPXDZPH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  26
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  164
• 氢给体数：
  0
• 氢受体数：
  8

文献信息

• [EN] HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME<br/>[FR] POLYPEPTIDES TRÈS ACTIFS ET PROCÉDÉS POUR LES PRÉPARER ET LES UTILISER
  申请人：LONGEVITY BIOTECH INC

  公开号：WO2011133948A2

  公开（公告）日：2011-10-27

  This invention relates to novel compositions comprising analogs of naturally occurring polypeptides, wherein the analog comprises an a-amino acid and at least one β- amino acid. Administration of the compositions may be used for effecting treatment or prevention of a plurality of disease states caused by dysfunctional biochemical or biological pathways. The compositions and methods of this invention are particularly useful to identify novel therapeutic modulators of in-vivo receptor activity with extended half-lives and relevant bioactivity as compared to the naturally translated polypeptides upon which the analogs are derived.