2-Hydroxy-1-heptadecyl-benzol | 96850-26-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 2-Hydroxy-1-heptadecyl-benzol
• 英文别名: 2-Heptadecyl-phenol；2-Heptadecylphenol
• CAS: 96850-26-9
• 化学式: C₂₃H₄₀O
• 分子量: 332.57
• InChiKey: SXDAKEUVFPZBQR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10.5
• 重原子数：
  24
• 可旋转键数：
  16
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.74
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  1-hexadecylmagnesium bromide 在 磷化氢 、 potassium hydrogensulfate 、 乙醚 、 氢碘酸 、 溶剂黄146 、 铂 作用下， 生成 2-Hydroxy-1-heptadecyl-benzol
  参考文献：
  名称：

  Backer; Haack, Recueil des Travaux Chimiques des Pays-Bas, 1941, vol. 60, p. 661,666

  摘要：

  DOI：

文献信息

• Synthesis and Structure-Activity Relationships of Phaffiaol and Related Antioxidants.
  作者：Shuji JINNO、Takaaki OKITA

  DOI：10.1248/cpb.46.1688

  日期：——

  Total synthesis of a novel long chain alkyl phenol, phaffiaol (1), a potent antioxidant isolated from Phaffia rhodozyma, was achieved via three reaction steps starting from 3, 5-dibromosalicylaldehyde (2). We also prepared several types of long chain alkyl phenol having different aromatic rings or different carbon length, and evaluated their antioxidative activity using the rabbit erythrocyte membrane ghost system. Amongst these compounds, the novel methoxy phenol derivatives (6c, d, 7) having a heptadecyl moiety at the ortho-position to the hydroxy group, were approximately 2 times more active than α-tocopherol. In addition, 4-methoxy-2-pentadexylphenol (10h), which has a 15-carbon length in the side chain moiety, showed the maximum activity.

  通过从3,5-二溴水杨醛（2）开始的三个反应步骤，实现了从Phaffia rhodozyma中分离得到的强效抗氧化剂phaffiaol（1）这一新型长链烷基酚的完全合成。我们还制备了几种具有不同芳环或不同碳链长度的长链烷基酚，并通过兔红细胞膜系统评估了它们的抗氧化活性。在这些化合物中，具有十七烷基侧链且位于羟基邻位的甲氧基酚衍生物（6c、d、7）的活性约为α-生育酚的两倍。此外，侧链具有15个碳原子的4-甲氧基-2-十五烷基酚（10h）显示出最高的活性。
• PROCESS FOR PREPARING AN ALKYLCYCLOHEXANOL ALKYLENE OXIDE ADDUCT
  申请人：——

  公开号：US20010051752A1

  公开（公告）日：2001-12-13

  The invention is a preparation process of alkylcyclohexanol alkylene oxide adduct which contains almost no alkylphenol alkylene oxide adduct 1) in the absence of a solvent, 2) in the presence of a saturated hydrocarbon solvent, or 3) in the presence of water. The invention can prepare alkylcyclohexanol alkylene oxide having a 200 ppm or less content of alkylphenol and alkylphenol alkylene oxide adduct. The alkylcyclohexanol alkylene oxide adduct obtained in the process of the invention has less ultraviolet absorption and fluorescence due to alkylphenol alkylene oxide adduct and is thus useful for spectrometric analysis of protein and further has excellent properties in the field of detergent and other common uses of surface active agents.

  本发明是一种制备含有几乎不含烷基苯酚烷氧基加合物的烷基环己醇烷氧基加合物的制备方法，该方法可以在以下条件下进行：1）无溶剂存在；2）存在饱和烃溶剂；或3）存在水。本发明可以制备出烷基环己醇烷氧基加合物，其烷基苯酚和烷基苯酚烷氧基加合物的含量低于200 ppm。由本发明方法得到的烷基环己醇烷氧基加合物由于烷基苯酚烷氧基加合物含量较低，因此具有较少的紫外吸收和荧光，因此在蛋白质光谱分析方面有用，并且在洗涤剂和其他表面活性剂的常见用途方面具有优异的性能。
• Process for preparing an alkylcyclohexanol alkyleneoxide adduct
  申请人：——

  公开号：US20030009061A1

  公开（公告）日：2003-01-09

  The invention is a preparation process of alkylcyclohexanol alkylene oxide adduct which contains almost no alkylphenol alkylene oxide adduct 1) in the absence of a solvent, 2) in the presence of a saturated hydrocarbon solvent, or 3) in the presence of water. The invention can prepare alkylcyclohexanol alkylene oxide having a 200 ppm or less content of alkylphenol and alkylphenol alkylene oxide adduct. The alkylcyclohexanol alkylene oxide adduct obtained in the process of the invention has less ultraviolet absorption and fluorescence due to alkylphenol alkylene oxide adduct and is thus useful for spectrometric analysis of protein and further has excellent properties in the field of detergent and other common uses of surface active agents.

  这项发明是一种制备含有几乎不含烷基苯酚烷基氧化物加合物的烷基环己醇烷基氧化物加合物的制备过程，可在以下条件下进行：1）无溶剂、2）有饱和烃溶剂的存在、或3）在水的存在下。该发明可以制备出含有200 ppm或更少烷基苯酚和烷基苯酚烷基氧化物加合物的烷基环己醇烷基氧化物加合物。在该发明的过程中获得的烷基环己醇烷基氧化物加合物由于烷基苯酚烷基氧化物加合物的紫外吸收和荧光较少，因此在蛋白质光谱分析中有用，并且在洗涤剂和其他常见表面活性剂的领域具有优异的性能。
• Polycarbonate resin compositon and molded article
  申请人：Mitsuhashi Kenichi

  公开号：US20050261414A1

  公开（公告）日：2005-11-24

  Provided are a polycarbonate resin composition which does not contain halogen and phosphorus as a flame retardant component and which is excellent in a fluidity while maintaining a flame resistance, a heat resistance and an impact resistance and a molded article thereof. The polycarbonate resin composition comprises (A) 60 to 97 mass % of an aromatic polycarbonate resin composition and 3 to 40 mass % of (B) an acrylonitrile-styrene base resin having a melt flow rate (MFR) of 5 or more at 200° C. and a load of 5 kg, wherein it is blended with 0 to 37 mass parts of (C) an impact resistance-improving agent, 0 to 3 mass parts of (D) an organic alkali metal salt and/or an organic alkali earth metal salt, 0 to 3 mass parts of (E) a functional group-containing silicone compound, 0 to 55 mass parts of (F) an inorganic filler and 0 to 2 mass parts of (G) a polyfluoroolefin resin each per total 100 mass parts of (A) and (B).

  提供一种聚碳酸酯树脂组合物，不含卤素和磷作为阻燃组分，同时保持耐火性、耐热性和抗冲击性，以及其模制品。该聚碳酸酯树脂组合物包括(A) 60-97质量％的芳香族聚碳酸酯组合物和3-40质量％的(B) 丙烯腈-苯乙烯基树脂，其在200℃和5千克的负荷下具有熔融流动速率（MFR）为5或更高。其中，它与(C) 抗冲击性改进剂的0-37质量部分混合，以及每100质量部分(A)和(B)中的0-3质量部分(D) 有机碱金属盐和/或有机碱土金属盐，0-3质量部分(E) 含有功能基团的硅氧烷化合物，0-55质量部分(F) 无机填料和0-2质量部分(G) 聚氟烯烃树脂。
• POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE
  申请人：MITSUHASHI Kenichi

  公开号：US20080076866A1

  公开（公告）日：2008-03-27

  Provided are a polycarbonate resin composition which does not contain halogen and phosphorus as a flame retardant component and which is excellent in a fluidity while maintaining a flame resistance, a heat resistance and an impact resistance and a molded article thereof.

  提供了一种聚碳酸酯树脂组合物，该组合物不含卤素和磷作为阻燃组分，同时具有出色的流动性能，同时保持着耐火性、耐热性和抗冲击性，以及其成型品。