diethyl 4-nitro-benzoylphosphonate | 2942-55-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: diethyl 4-nitro-benzoylphosphonate
• 英文别名: p-Nitro-benzoyl-phosphonsaeure-diaethylester；Diethoxyphosphoryl-(4-nitrophenyl)methanone
• CAS: 2942-55-4
• 化学式: C₁₁H₁₄NO₆P
• 分子量: 287.209
• InChiKey: PISSRYQDQHBDOW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  19
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  98.4
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  diethyl (hydroxy(4-nitrophenyl)methyl)phosphonate 在 potassium permanganate 作用下， 以 苯 为溶剂， 反应 12.0h， 以95%的产率得到diethyl 4-nitro-benzoylphosphonate
  参考文献：
  名称：

  通过在无溶剂条件下用中性氧化铝负载的高锰酸钾（NASPP）和高锰酸钾在无水苯中氧化α-羟基膦酸酯来制备α-酮膦酸酯

  摘要：

  在无溶剂条件下，通过在干苯中的高锰酸钾或中性氧化铝负载的高锰酸钾（NASPP），可以将各种类型的α-羟基膦酸酯高产率地转化为α-酮膦酸酯。

  DOI：

  10.1016/s0040-4039(01)02146-3

文献信息

• High yield preparation of α-ketophosphonates by oxidation of α-hydroxyphosphonates with zinc dichromate trihydrate (ZnCr2O7·3H2O) under solvent-free conditions
  作者：Habib Firouzabadi、Nasser Iranpoor、Sara Sobhani、Ali-Reza Sardarian

  DOI：10.1016/s0040-4039(01)00712-2

  日期：2001.6

  Various types of α-hydroxyphosphonates were converted to α-ketophosphonates by zinc dichromate trihydrate in high yields and rates under solvent-free conditions.

  通过三水合重铬酸锌在无溶剂条件下以高收率和高产率将各种类型的α-羟基膦酸酯转化为α-酮膦酸酯。
• Surface-mediated solid-phase reactions: the preparation of acyl phosphonates by oxidation of 1-hydroxyphosphonates on the solid surface
  作者：Babak Kaboudin

  DOI：10.1016/s0040-4039(00)00323-3

  日期：2000.4

  Alumina-supported CrO3, under solvent-free conditions, was found to be an efficient oxidizing reagent for the preparation of acyl phosphonates from 1-hydroxyphosphonates. This method is an easy, rapid, and high-yielding reaction for the preparation of acyl phosphonates from 1-hydroxyphosphonates. (C) 2000 Elsevier Science Ltd. All rights reserved.
• A CONVENIENT AND MILD PROCEDURE FOR THE PREPARATION OF α-KETO PHOSPHONATES OF 1-HYDROXYPHOSPHONATES UNDER SOLVENT-FREE CONDITIONS USING MICROWAVE
  作者：Babak Kaboudin、Rahman Nazari

  DOI：10.1081/scc-100104822

  日期：2001.1

  The Reactions of 1-hydroxyphosphonates on the alumina-supported CrO3 are accelerated by microwave irradiation under solvent-free conditions to afford a high yielding synthesis of alpha -keto phosphonates.
• Preparation of α‐Ketophosphonates by Oxidation of α‐Hydroxyphosphonates with Chromium‐Based Oxidants
  作者：Habib Firouzabadi、Nasser Iranpoor、Sara Sobhani

  DOI：10.1081/scc-120030697

  日期：2004.12.31

  Various types of diethyl alpha-hydroxyphosphonates were efficiently converted to diethyl alpha-ketophosphonates by nicotinium dichromate (NDC), nicotinium chlorochromate (NCC), and isonicotinium dichromate (INDC) in high yields.
• PREPARATION OF α-KETOPHOSPHONATES BY OXIDATION OF α-HYDROXYPHOSPHONATES WITH PYRIDINIUM CHLOROCHROMATE (PCC)
  作者：Habib Firouzabadi、Nasser Iranpoor、Sara Sobhani

  DOI：10.1080/10426500490463925

  日期：2004.8

  Various types of diethyl alpha-hydroxyphosphonates were converted efficiently to their corresponding diethyl alpha-ketophosphonales by pyridinum. chlorochromate (PCC) without cleavage of C(O)-P bond in the absence of solvent or in. solution in high yields.