Allyl-(1-((S)-(benzenesulfonyl-methyl-amino)-methyl-phenyl-butyl)-piperidin-4-yl)carbamic acid, 4-nitro-benzyl ester | 502173-16-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Allyl-(1-((S)-(benzenesulfonyl-methyl-amino)-methyl-phenyl-butyl)-piperidin-4-yl)carbamic acid, 4-nitro-benzyl ester
• 英文别名: (4-nitrophenyl)methyl N-[1-[4-[benzenesulfonyl(methyl)amino]-3-methyl-3-phenylbutyl]piperidin-4-yl]-N-prop-2-enylcarbamate
• CAS: 502173-16-2
• 化学式: C34H42N4O6S
• 分子量: 634.8
• InChiKey: NNARXJVWUPPZIP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  45
• 可旋转键数：
  14
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  124
• 氢给体数：
  0
• 氢受体数：
  8

文献信息

• IRNA Agents Targeting CCR5 Expressing Cells And Uses Thereof
  申请人：Manoharan Muthiah

  公开号：US20080255345A1

  公开（公告）日：2008-10-16

  The invention relates to iRNA agents that preferably include a modification that targets CC chemokine receptor 5 (CCR5). The invention also relates to methods of making and using such modified iRNA agents.
• iRNA Agents Targeting CCR5 Expressing Cells And Uses Thereof
  申请人：Manoharan Muthiah

  公开号：US20110313144A1

  公开（公告）日：2011-12-22

  The invention relates to iRNA agents that preferably include a modification that targets CC chemokine receptor 5 (CCR5). The invention also relates to methods of making and using such modified iRNA agents.
• US8034921B2
  申请人：——

  公开号：US8034921B2

  公开（公告）日：2011-10-11